Abstract
This study examined the effect of exercise on plasma fibrinogen concentrations with
simultaneous measurements of plasma volume changes. Eight moderately active males
aged 26.6±3.6 years (mean±SD) completed maximal (VO2max) and submaximal (75% VO2max for 30 minutes) exercise trials separated by 7 days. Venous blood samples were
obtained at rest, immediately postexercise, and following 30 minutes of recovery.
Whole blood was analysed for haematocrit and haemoglobin, while citrated plasma was
assayed for fibrinogen levels. Values of haematocrit and haemoglobin before and after
exercise were utilised for the estimation of plasma volume changes. Plasma volume
decreased (p<0.05) immediately following both maximal (−17.7±5.1%) and submaximal (−14.3±4.1%)
exercise. Exercise resulted in decreased plasma fibrinogen levels (maximal exercise:
from 266.3±14.5 to 222.2±23.9 mg·dL−1; submaximal exercise: from 239.5±45.4 to 209.7±42.4 mg·dL−1) only when postexercise raw data were corrected for the contraction of plasma volume.
It is concluded therefore that changes in plasma volume in response to exercise should
be taken into account when interpreting exercise effects on plasma fibrinogen concentration.
Keywords
Abbreviations:
Hct, haematocrit (), Hb, haemoglobin (), ANOVA, analysis of variance ()To read this article in full you will need to make a payment
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Article info
Publication history
Published online: August 17, 2004
Accepted:
July 12,
1999
Received in revised form:
July 12,
1999
Received:
May 11,
1999
by Editor D. Prisco;Identification
Copyright
© 1999 Elsevier Science Ltd. Published by Elsevier Inc. All rights reserved.
