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Editorial Board
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| 1. Cancer and Thrombosis in Women |
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Author(s) |
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Thirty-day mortality rate in women with cancer and venous thromboembolism. Findings from the RIETE Registry
Abstract: The influence of the site of cancer on outcome in cancer women with venous thromboembolism (VTE) is poorly understood. Reliable information on its influence might facilitate better use of pr...
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Javier Trujillo-Santos,
José Manuel Casa,
Ignacio Casado,
Ángel Luis Samperiz,
Roberto Quintavalla,
Joan Carles Sahuquillo,
Manuel Monreal,
the RIETE Investigators
et al.
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S1-S4
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Prevention of VTE in women with cancer
Abstract: The prevention of venous thromboembolism (VTE) in women with cancer requires special consideration. The presence of cancer results in both non-surgical and surgical patients having increased...
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Alexander T. Cohen,
Jack O. Wills,
Nandini Bharathi,
Joel Vincente Solis
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S5-S8
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| 2. Pulmonary Embolism |
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Author(s) |
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Thromboprophylaxis after cesarean section: decision analysis
Abstract: Although venous thromboembolism (VTE) is the leading cause of maternal mortality in developed countries, the usefulness of preventive low-molecular weight heparin (LMWH) after cesarean secti...
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Marc Blondon
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S9-S12
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The diagnostic management of acute venous thromboembolism during pregnancy: recent advancements and unresolved issues
Abstract: Adequate diagnostic management of suspected venous thromboembolism (VTE) in pregnant women is of great importance. The diagnostic performance of clinical decision rules and D-dimer testing i...
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M. Tan,
M.V. Huisman
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S13-S16
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| 3. Biologic Basis of Hormonal Effects on Coagulation |
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Author(s) |
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Murine models of obesity and hormonal therapy
Abstract: Obesity is a common disorder, and related diseases such as diabetes, atherosclerosis, hypertension, cardiovascular disease and cancer are a major cause of mortality and morbidity in Westernt...
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H.R. Lijnen
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S17-S20
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Thrombin generation tests
Abstract: The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin a...
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Elisabetta Castoldi,
Jan Rosing
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S21-S25
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| 4. Hormonal Therapy and Thrombosis |
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Author(s) |
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Postmenopausal hormone therapy and venous thromboembolism
Abstract: Introduction: Hormone therapy (HT) is the most effective treatment to counteract menopauserelated symptoms. Because venous thromboembolism (VTE) is the main harmful effect of HT among young ...
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Valérie Olié,
Marianne Canonico,
Pierre-Yves Scarabin
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S26-S29
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Epidemiology of the contraceptive pill and venous thromboembolism
Abstract: Current users of combined oral contraceptives have an increased risk of venous thromboembolism. The risk appears to be higher during the first year of use and disappears rapidly once oral co...
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Philip C. Hannaford
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S30-S34
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Controversies in postpartum contraception: When is it safe to start oral contraceptives after childbirth?
Abstract: The timely initiation of contraception postpartum is an important consideration for breastfeeding and non-breastfeeding women; many women prefer oral contraceptive pills to other methods. In...
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Emily Jackson
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S35-S39
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| 5. Antiphospholipid Syndrome |
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Article Title |
Author(s) |
Pages |
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Mechanisms of anti-phospholipid antibody formation and action
Abstract: The antiphospholipid syndrome is an autoimmune disease characterised by the clinical features of recurrent thrombosis in the venous or arterial circulation and foetal losses in combination w...
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Philip G. de Groot
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S40-S42
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Role of tissue factor in pregnancy complications: crosstalk between coagulation and inflammation
Abstract: Bad pregnancy outcomes have been associated with increased activation of the coagulation cascade and inflammation, in particular the activation of the complement cascade. Recent studies have...
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Guillermina Girardi
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S43-S46
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Antiphospholipid syndrome: Unusual clinical presentations
Abstract: Although the typical thrombotic manifestations of antiphospholipid syndrome, and pregnancy complications, are well recognised, the literature is awash with reports of more obscure associatio...
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Mike Greaves
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S47-S50
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APS – controversies in diagnosis and management, critical overview of current guidelines
Abstract: Because the diagnosis of antiphospholipid syndrome is based on laboratory data, performance and interpretation of such tests is essential. Positivity in a single test among Lupus Anticoagula...
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Vittorio Pengo
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S51-S52
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| 6. Arterial Thrombosis |
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Vascular complications in diabetic pregnancy
Abstract: Until now, vascular complications in diabetic pregnancy are mainly related to hyperglycemia caused by type 1 diabetes (Type 1 DM). Progression of diabetic retinopathy (DR) occurs at least te...
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R. Kaaja
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S53-S55
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Anticoagulant therapy in pregnant women with mechanical prosthetic heart valves: no easy option
Abstract: The choice of anticoagulant agent for pregnant women with mechanical prosthetic heart valves introduces a clinical dilemma for women and the clinicians caring for them. Options include conti...
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Claire McLintock
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S56-S60
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Resistance to anti-platelet agents
Abstract: In the last few years, the concept of resistance to antiplatelet agents has been largely emphasized in the medical literature, although its definition is still uncertain. The real prevalence...
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Marco Cattaneo
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S61-S63
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| 7. Gestational Vascular Complications |
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Angiogenesis in gestational vascular complications
Abstract: Vascular endothelial growth factor (VEGF) is a key player in vasculogenesis and angiogenesis in the embryo, and essential in neovascularization in adults. Natural VEGF inhibitors such as sol...
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Simcha Yagel
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S64-S66
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Microparticles and pregnancy complications
Abstract: Microparticles (MPs) are shed from cell membranes of a variety of cells, promote thrombus formation, mediate pro-inflammatory effects and may cause endothelial dysfunction. Normal pregnancy ...
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Anat Aharon,
Benjamin Brenner
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S67-S71
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New insights into the etiology of preeclampsia: identification of key elusive factors for the vascular complications
Abstract: The incidence of preeclampsia is reduced by a third in smokers, but not in snuff users. Soluble Flt-1 (sFlt-1) and soluble endoglin (sEng) are increased prior to the clinical onset of preecl...
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Asif Ahmed
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S72-S75
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Anticoagulant prophylaxis for placenta mediated pregnancy complications
Abstract: Thrombophilias are not yet established as a cause of the placenta-mediated pregnancy complications (pregnancy loss, pre-eclampsia, small for gestational age and placental abruption). A throm...
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Marc A. Rodger
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S76-S80
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| 8. Unexplored Venous Thrombosis in Women |
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Author(s) |
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Recent findings in the epidemiology, diagnosis and treatment of superficial-vein thrombosis
Abstract: Recent data on lower-limb superficial-vein thrombosis (SVT) may substantially impact its clinical management. Thus, the clear confirmation that SVT is closely linked to deep-vein thrombosis ...
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Hervé Décousus,
Laurent Bertoletti,
Paul Frappé,
François Becker,
Asma El Jaouhari,
Patrick Mismetti,
Nathalie Moulin,
Emilie Presles,
Isabelle Quéré,
Alain Leizorovicz
et al.
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S81-S85
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Venous thrombosis at unusual site in women
Abstract: Several sex-related differences in the incidence rate, clinical presentation and outcomes of VTE were recently investigated. Gender-related risk factors, such as the use of oral contraceptiv...
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Erica Romualdi,
Walter Ageno
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S86-S88
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The post thrombotic syndrome
Abstract: More than one-third of women with deep venous thrombosis (DVT) will develop the postthrombotic syndrome (PTS), and 5-10% develop severe PTS, which can manifest as venous ulcers. Typical feat...
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Susan R. Kahn
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S89-S92
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| 9. Placental Hemostasis |
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Article Title |
Author(s) |
Pages |
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Is placental haemostasis relevant to recurrent implantation failure?
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Scott M. Nelson
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S93-S95
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Placental pathology in pregnancy complications
Abstract: Among pregnancy pathologies preeclampsia and fetal growth restriction are among the leading causes of maternal and perinatal mortality and morbidity. For both syndromes, the etiologies are s...
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Berthold Huppertz
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S96-S99
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| 10. Heparins in Pregnancy |
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Overview on guidelines and recommendations for generic low-molecular-weight heparins
Abstract: The first generic low-molecular-weight heparin (LMWH) was approved by the Food and Drug Administration (FDA) end of July 2010 for clinical use in all medical indications where the branded pr...
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Job Harenberg
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S100-S104
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Low-molecular-weight heparins have no place in recurrent miscarriage: Debate – For the motion
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Saskia Middeldorp
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S105-S109
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LMWH have no place in recurrent pregnancy loss: Debate – against the motion
Abstract: The SPIN and ALIFE intervention trials apparently support that LMWHs should not be advocated in patients with idiopathic RPL. There are however some concerns. Epidemiology implies that most ...
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Jean-Christophe R. Gris
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S110-S112
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| 11. Bleeding in Women and Neonates |
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Article Title |
Author(s) |
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Antifibrinolytics in women with menorrhagia
Abstract: Heavy menstrual bleeding is associated with increased local fibrinolysis. Antifibrinolytic agents have been used in women with menorrhagia with and without bleeding disorders, and have been ...
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Claire S. Philipp
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S113-S115
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Post-partum hemorrhage in women with rare bleeding disorders
Abstract: Post-partum hemorrhage (PPH) accounts for a substantial fraction of maternal deaths in the general population. Among all women, however, those affected with rare bleeding disorders (RBDs) re...
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Flora Peyvandi,
Marzia Menegatti,
Simona Maria Siboni
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S116-S119
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Neonatal IVH – mechanisms and management
Abstract: Intra-ventricular hemorrhage (IVH) occurs predominantly in very low birth weight premature infants. Survivors of severe IVH frequently experience long-term consequences including major neuro...
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Gili Kenet,
Amir A. Kuperman,
Tzipora Strauss,
Benjamin Brenner
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S120-S122
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| Abstracts |
| Oral presentations |
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Article Title |
Author(s) |
Pages |
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O.01a Impact of common thrombophilias and JAK2 V617F on pregnancy outcomes in unselected Italian women
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E. Grandone,
D. Colaizzo,
G. Tiscia,
P. Vergura,
F. Cappucci,
G.M. Maruotti,
L. Greco,
M. Margaglione,
P. Martinelli,
on behalf of PRENACEL study group
et al.
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S123
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O.01b All trans-retinoic acid modulates the procoagulant activity of human breast cancer cells
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A. Falanga,
L. Russo,
D. Balducci,
M. Marchetti
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S123
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O.02a Efficacy of obstetric thromboprophylaxis and long-term risk of recurrence of venous thromboembolism
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P.G. Lindqvist,
K. Bremme,
M. Hellgren
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S123-S124
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O.02b Magnetic resonance imaging and ultrasonography in diagnosis of pelvic vein thrombosis during pregnancy
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A. Hagman,
M. Torkzad,
K. Bremme,
M. Hellgren,
M.J. Eriksson,
T. Jörgensen,
K. Lund,
G. Sandgren,
L. Blomqvist,
P. Kälebo
et al.
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S124
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O.03a A microarray study on the effect of four hormone therapy regimens on gene transcription in leucocytes from healthy postmenopausal women
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A.E.A. Dahm,
A.L. Eilertsen,
J. Goeman,
O.K. Olstad,
R. Øvestebø,
P. Kierulf,
M.-C. Mowinchel,
G. Skretting,
P.M. Sandset
et al.
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S124
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O.03b SNPS in the SULT1E1 gene and the risk of oral contraceptive-associated venous thrombosis
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B.H. Stegeman,
H.L. Vos,
F.M. Heimerhorst,
A. van Hylckama Vlieg,
P.H. Reitsma,
F.R. Rosendaal
et al.
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S124
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O.04a Risk of VTE during combined oral contraceptive use and pregnancy in women with mild thrombophilia
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E.F.W. van Vlijmen,
N.J.G.M. Veeger,
S. Middeldorp,
K. Hamulyák,
M.H. Prins,
H.R. Büller,
K. Meijer
et al.
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S124
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O.04b Effect of the dose of oral treatment with 17beta-estradiol associated with dydrogesterone on thrombin generation in healthy postmenopausal women: a randomized double-blind placebo-controlled study
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G. Gerotziafas,
V. Galea,
A. Rousseau,
D. Torchin,
K.F. Zannad,
K. Lacut,
J. Demolis,
T. Simon,
I. Elalamy
et al.
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S125
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O.05a Antiphospholipid antibodies and the risk of intrauterine fetal death – Results of a case-control study
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L.B. Helgadóttir,
F.E. Skjeldestad,
A.F. Jacobsen,
P.M. Sandset,
E.M. Jacobsen
et al.
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S125
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O.05b Low molecular weight heparin actions on human endometrial angiogenesis
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N. Di Simone,
C. Tersigni,
F. Di Nicuolo,
S. D'Ippolito,
R. Castellani,
R. Marana,
J. Stinson
et al.
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S125
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O.06a Nocturnal variability of coagulation in gestational diabetes
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M. Pöyhönen-Alho,
R. Kaaja
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S125-S126
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0.06b Role of protein S and tissue factor pathway inhibitor in the development of APC resistance early in pregnancy
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S.N. Tchaikovski,
M.C.L.G.D. Thomassen,
S.D. Costa,
L.L.H. Peeters,
J. Rosing
et al.
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S126
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0.06C Oligoamenorrhea, high weight accrual rate, acanthosis and first trimester hypertriglyceridemia are independent predictors of preeclampsia
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S. Hoirisch Clapauch,
P.R. Benchimol-Barbosa
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S126
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0.07a Enoxaparin for the secondary prevention of placental vascular complications in women with severe pre-eclampsia: the pilot randomised controlled NOH-PE study
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J.C. Gris,
C. Chauleur,
P. Marès,
I. Quéré,
J.Y. Lefrant,
B. Haddad,
M. Dauzat
et al.
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S126
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0.07b Low molecular weight heparin versus no treatment in women with previous severe pregnancy complications and placental findings without thrombophilia
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M. Kupfermine,
E. Rimon,
A. Many,
S. Maslovitz,
J.B. Lessing,
R. Gamzu
et al.
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S126
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0.08a Prevalence and predictors for post-thrombotic syndrome (PTS) three to 16 years after first-time pregnancy related venous thrombosis – a population-based case-control study
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H.S. Wik,
A.F. Jacobsen,
L. Sandvik,
P.M. Sandset
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S127
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0.08b Reduced sensitivity to activated protein C in the absence of the factor V Leiden polymorphism is a risk factor for pregnancy related venous thrombosis
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A. Bergrem,
A.E.A. Dahm,
A.F. Jacobsen,
M.C. Mowinckel,
L. Sandvik,
P.M. Sandset
et al.
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S127
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0.09a Microparticles' effect on apoptosis, angiogenesis and migration in healthy and pathological pregnancies
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E. Shomer,
S. Katzenell,
Y. Zipori,
R.N. Sammour,
B. Brenner,
A. Aharon
et al.
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S127
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0.09b p45NF-E2 epigenetically represses Gcm1 in trophoblast cells, regulating syncytium formation, placental vascularization and embryonic growth
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M. Kashif,
A. Helwig,
M. Thati,
K. Shahzad,
H. Wang,
T. He,
S. Ranjan,
J. Wolter,
P.P. Nawroth,
B. Isermann
et al.
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S127
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0.10a Risk of PPH in women using therapeutic dosage of LMWH during pregnancy and puerperium
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H.M. Knol,
L. Schultinge,
J.J.H.M. Erwich,
N.J.G.M. Veeger,
H.C. Kluin-Nelemans,
K. Meijer
et al.
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S127-S128
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0.10b Low-molecular-weight heparin for prevention of obstetric complications in carriers of factor V Leiden or PT-G20210A mutation
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D. Tormene,
E. Grandone,
V. De Stefano,
G. Palareti,
G. Castaman,
M. Margaglione,
A. Ciminello,
L. Valdrè,
A. Tosetto,
P. Simioni
et al.
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S128
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0.11a Tranexamic acid reduces blood loss in post-partum haemorrhage
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A.-S. Ducloy-Bouthors,
A. Duhameir,
S. Susenr,
F. Broisin,
C. Huissoud,
H. Keita-meyer,
L. Mandelbrot,
N. Tillouche,
S. Fontaine,
F. le Goueff,
S. Depret-Mosser,
B. Jude,
the EXADELI centres and investigators (annex 1)
et al.
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S128
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0.11b Gynaecological and obstetric bleeding in moderate and severe Von Willebrand Disease
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E.M. de Wee,
H.M. Knol,
E.P. Mauser-Bunschoten,
J.G. van der Bom,
M.E.L. Degenaar-Dujardin,
J.C.J. Eikenboom,
K. Fijnvandraat,
A. de Goede-Bolder,
B. Laros-van Gorkom,
P.F. Ypma,
S. Zweegman,
K. Meijer,
F.W.G. Leebeek,
for the WiN study group
et al.
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S129
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| Poster Presentations |
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Article Title |
Author(s) |
Pages |
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P.1 Thromboprophylaxis in pregnancy in women with increased risk of venous thromboembolism
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P. Dulííck,
J. Malý,
M. Pecka,
M. Beránek
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S129
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P.2 Cerebral venous thrombosis risk factors
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M. Kostal,
P. Dulicek,
J. Maly,
D. Krajickova,
F. Vrbacky,
M. Beranek
et al.
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S129
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P.3 ETP – a sensitive marker of haemostasis in women undergoing in vitro fertilization
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E. Westerlund,
P. Henriksson,
N.H. Wallen,
O. Hovatta,
M. Blombäck,
A. Antovic
et al.
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S129-S130
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P.4 Preeclampsia as a risk factor for postnatal pulmonary embolism
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B. Wibaut,
N. Trillot,
P. Deruelle,
P.Y. Hatron,
M. Lambert,
A.S. Ducloy-Bouthors
et al.
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S130
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P.5 Occurrence of obstetric and thromboembolic complications in family members of women with common inherited thrombophilias
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M. Villani,
D. Colaizzo,
E. Chinni,
F. Cappucci,
L. Fischetti,
M. Margaglione,
E. Grandone
et al.
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S130
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