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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Levels of fibrinogen and thromboelastometry fibrin polymerisation following treatment with desmopressin (DDAVP)
DOI: 10.1016/j.thromres.2012.01.006
Introduction. Patients who have received platelet inhibitory drugs may constitute a challenge in management of perioperative bleeding . Administration of DDAVP has been proposed to be effective in par...
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Benny Sørensen,
Gary Moore,
Gerald Hochleitner,
Christian Fenger-Eriksen
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Correspondence
(In Press Corrected Proof)
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01 February 2012 |
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Factors associated with the failure of clopidogrel dose-adjustment according to platelet reactivity monitoring to optimize P2Y12-ADP receptor blockade
DOI: 10.1016/j.thromres.2011.12.038
Abstract: Introduction: Inter-individual variability in clopidogrel responsiveness is dependent on genetic polymorphisms. We aimed to investigate the impact of 3 genetic polymorphisms involved in clop...
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Laurent Bonello,
Laurence Camoin-Jau,
Julien Mancini,
Jacques Bessereau,
Charlotte Grosdidier,
Marie-Christine Alessi,
Michel Ostorero,
Françoise Dignat-George,
Franck Paganelli
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Continuous thrombin infusion leads to a bleeding phenotype in sheep
DOI: 10.1016/j.thromres.2011.09.019
Abstract: Background: In addition to a recognized role in the coagulation cascade and haemostasis, thrombin is known to have multiple functions. We aimed to establish an ovine model to study thrombin ...
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Jolanta M. Siller-Matula,
Ingrid Miller,
Manfred Gemeiner,
Roberto Plasenzotti,
Guenther Bayer,
Ildiko Mesteri,
Astrid Fabry,
Karin Petroczi,
Katharina Nöbauer,
Ebrahim Razzazi-Fazeli,
Sébastien Planchon,
Jenny Renaut,
Peter Quehenberger,
Edgar Selzer,
Bernd Jilma
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Incomplete resolution of deep vein thrombosis under reduced flow conditions
DOI: 10.1016/j.thromres.2012.01.004
Abstract: Introduction: Post-thrombotic syndrome is a major complication of deep vein thrombosis (DVT), occurring in up to 1/3 of first-episode DVT patients. Non-ambulatory patients have increased ris...
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Brian C. Cooley,
Chao-Ying Chen,
Ryan Hess,
Gregory Schmeling
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Prospective Study of the Frequency and Outcomes of Patients with Suspected Pulmonary Embolism Administered Heparin Prior to Confirmatory Imaging
DOI: 10.1016/j.thromres.2012.01.005
Abstract: Objectives: The administration of empiric systemic anticoagulation (ESA) before confirmatory radiographic testing in patients with suspected pulmonary embolism (PE) may improve outcomes, but...
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Jeffrey A. Kline,
Michael R. Marchick,
Christopher Kabrhel,
D. Mark Courtney
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Foreword
DOI: 10.1016/j.thromres.2011.12.037
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Giovanni de Gaetano,
Chiara Cerletti
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Miscellaneous
(In Press Corrected Proof)
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27 January 2012 |
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The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets
DOI: 10.1016/j.thromres.2011.12.021
Abstract: Introduction: Arterial thrombi contain more platelets than venous thrombi and are more resistant to fibrinolysis. This resistance could partly be due to plasminogen activator inhibitor 1 (PA...
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Martina Nylander,
Abdimajid Osman,
Sofia Ramström,
Emma Åklint,
Anders Larsson,
Tomas L. Lindahl
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Effect of the Factor Xa Inhibitor Rivaroxaban on Arterial Thrombosis in Wild-Type and Apolipoprotein E-Deficient Mice
DOI: 10.1016/j.thromres.2012.01.002
Abstract: Rivaroxaban is a potent and specific direct inhibitor of coagulation factor Xa. Recent studies have highlighted its effectiveness in the prevention of venous thrombosis and embolic stroke du...
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Nana-Maria Wagner,
Tobias Dressel,
Katrin Schäfer,
Stavros Konstantinides
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Podoplanin expression in advanced atherosclerotic lesions of human aortas
DOI: 10.1016/j.thromres.2012.01.003
Abstract: Thrombus formation on disrupted atherosclerotic lesion is a key mechanism of cardiovascular events. Podoplanin (Aggrus), expressed on the surface of several tumor cells, is an endogenous lig...
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Kinta Hatakeyama,
Mika Kato Kaneko,
Yukinari Kato,
Tetsunori Ishikawa,
Kensaku Nishihira,
Yuta Tsujimoto,
Yoshisato Shibata,
Yukio Ozaki,
Yujiro Asada
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Bridging with the Low molecular weight heparin certoparin in patients requiring temporary discontinuation of oral anticoagulation – the non-interventional, retrospective REMEMBER study
DOI: 10.1016/j.thromres.2011.12.039
Abstract: Background: Bridging of a temporal discontinuation of oral anticoagulation with low molecular weight heparins (LMWH) is common practice. Specific data on the LMWH certoparin are however limi...
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Ralf Eisele,
Nima Melzer,
Cornelia Englert,
Peter Bramlage,
Michael Spannagl
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Evaluation of multiple electrode aggregometry in whole blood using Multiplate® Mini Test cells
DOI: 10.1016/j.thromres.2011.12.032
Abstract: Multiple electrode aggregometry (MEA) enables rapid platelet function testing in whole blood using 600 μL disposable standard test cells (STC). However, newly available 350μL mini test cells...
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Kurtis R. Lee,
Veerle J.E. Verheyden,
Andrew D. Mumford
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Thrombosis and Acute coronary syndrome
DOI: 10.1016/j.thromres.2011.12.026
Abstract: Acute coronary syndromes (ACS) represent the main clinical manifestation of atherosclerotic progression in the coronary district. Thrombosis plays a critical role in the patho-anatomical of ...
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Rosanna Abbate,
Gabriele Cioni,
Ilaria Ricci,
Marco Miranda,
Anna Maria Gori
et al.
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Review article
(In Press Corrected Proof)
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27 January 2012 |
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Proteomics: Bases for protein complexity understanding
DOI: 10.1016/j.thromres.2011.12.035
Abstract: In the post genomic era we became aware that the genomic sequence and protein functions cannot be correlated. One gene can encode multiple protein functions mainly because of mRNA splice var...
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Domenico Rotilio,
Anna Della Corte,
Marco D'Imperio,
Walter Coletta,
Simone Marcone,
Cristian Silvestri,
Lucia Giordano,
Michela Di Michele,
Maria Benedetta Donati
et al.
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Review article
(In Press Corrected Proof)
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27 January 2012 |
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Assessment of a Cohort of Primarily Pediatric Patients with a Presumptive Diagnosis of Type 1 von Willebrand Disease with a Novel High Shear Rate, Non-citrated Blood Flow Device
DOI: 10.1016/j.thromres.2011.12.016
Abstract: Background: A precise approach to the diagnosis of von Willebrand disease (vWD) remains elusive. One important reason is that vWD is a blood flow‐related disorder: a vW Factor‐platelet GPIb ...
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Eric F. Grabowski,
Marjorie A. Curran,
Elizabeth M. Van Cott
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Thrombosis and cancer: 40 years of research
DOI: 10.1016/j.thromres.2011.12.022
Abstract: We have taken here the task to go back to a brief history concerning the evolution of the concept of “cancer and thrombosis” according to the experience accumulated by our group in the last ...
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Maria Benedetta Donati,
Roberto Lorenzet
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Review article
(In Press Corrected Proof)
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24 January 2012 |
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Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: A placebo-controlled study in rats
DOI: 10.1016/j.thromres.2011.12.029
Abstract: Introduction: Off-target effects of novel antiplatelet agents due to their potential clinical benefits are currently an area of intensive investigation. We aimed to compare the effects of di...
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Grzegorz Grzesk,
Marek Kozinski,
Eliano Pio Navarese,
Marek Krzyzanowski,
Elzbieta Grzesk,
Aldona Kubica,
Jolanta Maria Siller-Matula,
Fausto Castriota,
Jacek Kubica
et al.
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Old and new oral anticoagulants for venous thromboembolism and atrial fibrillation: A review of the literature
DOI: 10.1016/j.thromres.2011.12.014
Abstract: Heparin, fondaparinux and vitamin K antagonists (VKAs) are effective for the prevention and treatment of venous thromboembolism. VKAs reduce by almost 60% the rate of cardioembolic complicat...
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Cecilia Becattini,
Maria Cristina Vedovati,
Giancarlo Agnelli
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Review article
(In Press Corrected Proof)
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24 January 2012 |
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Mean platelet volume increases with aging in a large population study
DOI: 10.1016/j.thromres.2011.12.031
We read with interest the article of Demirin et al., who investigated the mean platelet volume (MPV) in a cohort of 326 healthy subjects by using a CELL-DYN 3700 SL analyzer (Abbott Diagnostics) . It ...
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Giuseppe Lippi,
Tiziana Meschi,
Loris Borghi
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Correspondence
(In Press Corrected Proof)
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20 January 2012 |
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Novel management of anticoagulant resistant thrombotic hypodysfibrinogenaemia
DOI: 10.1016/j.thromres.2011.12.027
Abstract: Individuals with hypodysfibrinogenaemia and recurrent thrombosis are rarely encountered and there is no consensus regarding long-term management. Guidelines available suggest that oral antic...
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C. Rea,
B.J. Hunt
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Full-length article
(In Press Corrected Proof)
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20 January 2012 |
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Bivalirudin is inferior to heparin in preservation of intraoperative autologous blood
DOI: 10.1016/j.thromres.2011.12.024
Abstract: Introduction: Bivalirudin is used as an alternative to heparin in cardiac surgery, and may be superior to heparin with regard to platelet function. Bivalirudin however, is prone to cleavage ...
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Rolf C.G. Gallandat Huet,
Vladimir Cernak,
Adrianus J. de Vries,
Ton Lisman
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Full-length article
(In Press Corrected Proof)
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20 January 2012 |
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Sustained heparin effect contributes to reduced plasma thrombin generation capacity early after cardiac surgery
DOI: 10.1016/j.thromres.2011.12.025
Abstract: Introduction: Thrombin is a key component in the coagulation cascade, and impaired thrombin generation has been linked to increased bleeding after surgical procedures. The aim was to evaluat...
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Vladimir Radulovic,
Monica Hyllner,
Lisa Ternström,
Martin Karlsson,
Anders Bylock,
Kenny M. Hansson,
Fariba Baghaei,
Anders Jeppsson
et al.
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Full-length article
(In Press Corrected Proof)
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20 January 2012 |
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Development and application of an automated chromogenic thrombin generation assay that is sensitive to defects in the protein C pathway
DOI: 10.1016/j.thromres.2011.12.034
Abstract: Background: Activated protein C resistance (APCR) within a thrombin generation test (TGT) system is associated with an increased risk of venous thromboembolism (VTE). However, application of...
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Laura Green,
Omid Safa,
Samuel J. Machin,
Ian J. Mackie,
Kim Ryland,
Hannah Cohen,
Andrew S. Lawrie
et al.
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Full-length article
(In Press Corrected Proof)
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20 January 2012 |
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The SISET incorrectly cited the JAAM DIC scoring system
DOI: 10.1016/j.thromres.2011.12.036
Dr Gando suggests to replace the JAAM score as currently reported in Table 1 of the Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET) on the diagnosis and treatment of dissemina...
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Marcello Di Nisio,
Francesco Baudo,
Benilde Cosmi,
Armando D'Angelo,
Andrea De Gasperi,
Alessandra Malato,
Mario Schiavoni,
Alessandro Squizzato
et al.
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Correspondence
(In Press Corrected Proof)
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19 January 2012 |
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Association between adiponectin gene polymorphisms and coronary artery disease across different populations
DOI: 10.1016/j.thromres.2011.12.028
Abstract: Objective: Many studies have suggested that adiponectin gene might be involved in the development of coronary artery disease (CAD). However, the results have been inconsistent. In this study...
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Liang Zhou,
Bo Xi,
Yuan Wei,
Haiyan Pan,
Wanshui Yang,
Weihua Shen,
Yixiang Li,
Jianguang Cai,
Hui Tang
et al.
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Full-length article
(In Press Corrected Proof)
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19 January 2012 |
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A case series of five episodes of massive LMWH non-fatal self-induced overdose in a single patient
DOI: 10.1016/j.thromres.2011.12.033
Low molecular weight heparins (LMWH) are frequently used for the prophylaxis and treatment of venous thromboembolic diseases (VTE). Their subcutaneous administration in fixed doses has made possible t...
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Jacob Odeberg,
Anders Carlsson,
Caroline Hällsjö-Sander,
Anna Ågren
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Correspondence
(In Press Corrected Proof)
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19 January 2012 |
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Effect of Hawthorn (Crataegus aronia syn. Azarolus (L)) on Platelet Function in Albino Wistar Rats
DOI: 10.1016/j.thromres.2012.01.001
Abstract: Objective: This study was designed to investigate the possible antiplatelet effect of aqueous whole-plant C. aronia syn: Azarolus (L) extract using Wistar albino rats as a model. Materials a...
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Abdullah S. Shatoor,
Hesham Soliman,
Fahaid Al-Hashem,
Basiouny El- Gamal,
Adel Othman,
Nadia El-Menshawy
et al.
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Full-length article
(In Press Corrected Proof)
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19 January 2012 |
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Characteristics of Fibrin Formation and Clot Stability in Individuals with Congenital Type IIb Protein C Deficiency
DOI: 10.1016/j.thromres.2011.12.020
Abstract: Many studies have shown that unregulated or excessive thrombin formation is potentially a cause of thrombosis; however, studies examining processes that contribute to fibrin stabilization in...
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J.H. Foley,
L. Ferris,
K.E. Brummel-Ziedins
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Evaluation of the Stratus® CS Acute Care™ D-dimer assay (DDMR) using the Stratus® CS STAT Fluorometric Analyzer: A prospective multisite study for exclusion of pulmonary embolism and deep vein thrombosis
DOI: 10.1016/j.thromres.2011.12.015
Abstract: Background: D-dimer testing is an integral part of the diagnostic algorithm in excluding patients with venous thromboembolism. In this study, we prospectively evaluated the Stratus DDMR D-di...
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Robert C. Gosselin,
Jogin R. Wu,
Kandice Kottke-Marchant,
Dirk Peetz,
Douglas J. Christie,
Heidrun Muth,
Edward Panacek
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters
DOI: 10.1016/j.thromres.2011.12.023
Abstract: Introduction: Total hip/knee replacement surgery (THR/TKR respectively) is associated with an increased risk of venous thromboembolism. Dabigatran is recommended as a thromboprophylactic age...
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Laura Green,
Andrew S. Lawrie,
Rahul Patel,
Robert C.M. Stephens,
Ian J. Mackie,
Andrew Chitolie,
Fares S. Haddad,
Samuel J. Machin
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Platelet-leukocyte deregulated interactions foster sterile inflammation and tissue damage in immune-mediated vessel diseases
DOI: 10.1016/j.thromres.2011.12.001
Summary: Platelets and leukocytes co-localize and interact at sites of vessel injury, haemorrhage, thrombosis and inflammation. Recent studies have highlighted the role of local cues in the interactio...
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Norma Maugeri,
Mattia Baldini,
Giuseppe A. Ramirez,
Patrizia Rovere-Querini,
Angelo A. Manfredi
et al.
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Review article
(In Press Corrected Proof)
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16 January 2012 |
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PDE4 Regulates Tissue Plasminogen Activator Expression of Human Brain Microvascular Endothelial Cells
DOI: 10.1016/j.thromres.2011.12.008
Abstract: Introduction: Factors regulating brain tissue plasminogen activator (tPA) are pertinent for stroke. Recent observations have suggested a role for the phosphodiesterase-4 (PDE4) pathway in st...
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Fan Yang,
Shuo Liu,
Chuanhui Yu,
Shur-Jen Wang,
Annlia Paganini-Hill,
Mark J. Fisher
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Interleukin-10 promoter microsatellite polymorphisms influence the immune response to heparin and the risk of heparin-induced thrombocytopenia
DOI: 10.1016/j.thromres.2011.09.033
Abstract: Introduction: Heparin-induced thrombocytopenia (HIT) results from an atypical immune response with synthesis of IgG antibodies (Abs) to platelet factor 4/heparin complexes (PF4/H), and proba...
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Claire Pouplard,
Pascale Cornillet-Lefebvre,
Redha Attaoua,
Dorothée Leroux,
Carinne Lecocq-Lafon,
Jérôme Rollin,
Florin Grigorescu,
Philippe Nguyen,
Yves Gruel
et al.
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Full-length article
(In Press Corrected Proof)
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13 January 2012 |
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Endothelial progenitor cells and thrombosis
DOI: 10.1016/j.thromres.2011.12.011
Abstract: The remodelling of existing vessels (i.e. angiogenesis) and the “de novo” vessel formation (i.e. vasculogenesis) occur not only during the embryonic development but also over the entire post...
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Eugenia Rosa Nuzzolo,
Maria Grazia Iachininoto,
Luciana Teofili
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Review article
(In Press Corrected Proof)
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12 January 2012 |
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Blood platelet production and morphology
DOI: 10.1016/j.thromres.2011.11.042
Abstract: Circulating platelets are highly specialized cells produced by megakaryocytes (Mks) that participate in hemostatic and inflammatory functions. Despite their critical role little is known abo...
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Alessandro Malara,
Alessandra Balduini
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Review article
(In Press Corrected Proof)
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09 January 2012 |
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Concomitant use of medication with antiplatelet effects in patients receiving either rivaroxaban or enoxaparin after total hip or knee arthroplasty
DOI: 10.1016/j.thromres.2011.12.005
Abstract: Introduction: The RECORD programme compared oral rivaroxaban with enoxaparin for prevention of venous thromboembolism after elective total hip or knee replacement. This analysis compared the...
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Bengt I. Eriksson,
Nadia Rosencher,
Richard J. Friedman,
Martin Homering,
Ola E. Dahl
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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A Randomized Controlled Trial of Empiric Warfarin Dose Reduction with the Initiation of Doxycycline Therapy
DOI: 10.1016/j.thromres.2011.12.017
Abstract: Background: When interacting medications, such as doxycycline, are initiated during warfarin therapy, one method to correct for non-therapeutic international normalized ratio (INR) is adjust...
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Mary Beth Dowd,
Kellie A. Kippes,
Daniel M. Witt,
Thomas Delate,
Kerri Martinez
et al.
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Critical role of factors II and X during coumarin anticoagulation and their combined measurement with a new Fiix-prothrombin time
DOI: 10.1016/j.thromres.2011.12.013
Abstract: Vitamin K antagonists (VKA) are monitored with prothrombin time (PT) based assays that are equally sensitive to reductions in factors II, VII or X. We compared the effect of vitamin K depend...
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Brynja R. Gudmundsdottir,
Charles W. Francis,
Alexia M. Bjornsdottir,
Moa Nellbring,
Pall T. Onundarson
et al.
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Pioglitazone inhibits platelet function and potentiates the effects of aspirin: A prospective observation study
DOI: 10.1016/j.thromres.2011.12.019
Abstract: Background: Thiazolidinediones (TZDs) are agonists of PPARγ and exert beneficial metabolic effects in patients with diabetes. They may also affect platelet function. Objectives: To character...
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John Mongan,
Hanna Z. Mieszczanska,
Brian H. Smith,
Susan P. Messing,
Richard P. Phipps,
Charles W. Francis
et al.
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Global haemostasis assays, from bench to bedside
DOI: 10.1016/j.thromres.2011.12.006
Abstract: Bleeding and thrombosis are the ultimate clinical outcomes of aberrations in the haemostatic process. Haemostasis prevents excessive blood loss due to the effort of various compartments like...
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Mark van Geffen,
Waander L. van Heerde
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Review article
(In Press Corrected Proof)
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05 January 2012 |
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Prognostic significance of adhesion molecules (sICAM-1, sVCAM-1) and VEGF in colorectal cancer patients
DOI: 10.1016/j.thromres.2011.12.004
Abstract: Introduction: Adhesion molecules take part in the interaction between host cells and cancer cells. In the current study the relationship between the soluble adhesion molecules sICAM-1 and sV...
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Violetta Dymicka-Piekarska,
Katarzyna Guzinska-Ustymowicz,
Adam Kuklinski,
Halina Kemona
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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A microarray study on the effect of four hormone therapy regimens on gene transcription in whole blood from healthy postmenopausal women
DOI: 10.1016/j.thromres.2011.12.009
Abstract: Background: Postmenopausal hormone therapy is associated with many diseases and conditions, e.g., cardiovascular diseases and asthma, but the underlying molecular mechanisms are incompletely...
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Anders E.A. Dahm,
Anette L. Eilertsen,
Jelle Goeman,
Ole Kristoffer Olstad,
Reidun Øvstebø,
Peter Kierulf,
Marie-Christine Mowinckel,
Grethe Skretting,
Per Morten Sandset
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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ABCB1 C3435T polymorphism and risk of adverse clinical events in clopidogrel treated patients: A meta-analysis
DOI: 10.1016/j.thromres.2011.12.003
Abstract: Introduction: The ABCB1 C3435T polymorphism limits oral bioavailability of clopidogrel and may influence prognosis of patients treated with clopidogrel. Several studies have examined the ass...
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Man Luo,
Jiaoxing Li,
Xiaowei Xu,
Xunsha Sun,
Wenli Sheng
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Platelet Oxidative Stress and Thrombosis
DOI: 10.1016/j.thromres.2011.12.002
Abstract: Experimental and clinical studies support the pivotal role played by reactive oxidant species in the mechanism of platelet activation. This effect is achieved via multiple pathways, includin...
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Francesco Violi,
Pasquale Pignatelli
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Review article
(In Press Corrected Proof)
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03 January 2012 |
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Non-fatal cardiovascular disease, malignancies, and other co-morbidity in adult haemophilia patients
DOI: 10.1016/j.thromres.2011.12.012
Abstract: Introduction: With increasing life expectancy, more haemophilia patients will be confronted with age-related problems. To ensure optimal care, it is important to know the occurrence of both ...
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Dietje E. Fransen van de Putte,
Kathelijn Fischer,
Astrid E. Pulles,
Goris Roosendaal,
Douwe H. Biesma,
Roger E.G. Schutgens,
Eveline P. Mauser-Bunschoten
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Diversity of Human Plasma Protein C Inhibitor
DOI: 10.1016/j.thromres.2011.11.035
Abstract: Protein C inhibitor was purified from human plasma by use of a dermatan sulfate or heparin column, followed by hydroxyapatite, gel filtration and ion exchange columns. A dimer of protein C i...
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Akio Saito
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Full-length article
(In Press Corrected Proof)
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30 December 2011 |
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Absence of JAK2V617F mutation in Chinese deep vein thrombosis patients without myeloproliferative neoplasms
DOI: 10.1016/j.thromres.2011.12.018
Deep vein thrombosis (DVT) is one of the most common health disorders and leads to significant morbidity and mortality. The reported annual incidence of venous thromboembolism (VTE) is approximately 1...
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Bingfei Dong,
Yang Zhang,
Xueqi Fu,
Guangyi Wang
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Correspondence
(In Press Corrected Proof)
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26 December 2011 |
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Factor XIII, clot structure, thrombosis
DOI: 10.1016/j.thromres.2011.11.040
Abstract: Blood coagulation factor XIII (FXIII) is a tetrameric protein consisting of two catalytic A (FXIII-A) and two carrier/inhibitory B (FXIII-B) subunits. It is a zymogen, which becomes transfor...
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Zsuzsa Bagoly,
Zsuzsa Koncz,
Jolán Hársfalvi,
László Muszbek
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Review article
(In Press Corrected Proof)
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26 December 2011 |
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Animal models of trauma-induced coagulopathy
DOI: 10.1016/j.thromres.2011.11.053
Abstract: Resurgent study of trauma-induced coagulopathy (TIC) has delivered considerable improvements in survival after injury. Robust, valid and clinically relevant experimental models of TIC are es...
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Daniel Frith,
Mitchell J. Cohen,
Karim Brohi
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Review article
(In Press Corrected Proof)
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26 December 2011 |
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Heparin modulates the conformation and signaling of platelet integrin αIIbβ3
DOI: 10.1016/j.thromres.2011.11.054
Abstract: Introduction: The glycosaminoglycan heparin has been shown to bind to platelet integrin αIIbβ3 and induce platelet activation and aggregation, although the relationship between binding and a...
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Mayumi Yagi,
Jacqueline Murray,
Kurt Strand,
Scott Blystone,
Gianluca Interlandi,
Yasuo Suda,
Michael Sobel
et al.
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Hematologic malignancies and thrombosis
DOI: 10.1016/j.thromres.2011.11.034
Abstract: Patients with hematologic malignancies have an increased risk of venous thromboembolism (VTE), particularly at diagnosis and during the treatment with chemotherapy, asparaginase or immunomod...
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F. Elice,
F. Rodeghiero
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Review article
(In Press Corrected Proof)
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26 December 2011 |
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Tissue factor/TFPI and blood cells
DOI: 10.1016/j.thromres.2011.11.049
Abstract: Vascular injury-induced access of blood to tissue factor (TF) leads to the formation of a TF-FVII/FVIIa complex and the triggering of blood coagulation. The activated TF-dependent pathway is...
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Bjarne Østerud
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Review article
(In Press Corrected Proof)
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26 December 2011 |
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Factor XI: Hemostasis, Thrombosis, and Antithrombosis
DOI: 10.1016/j.thromres.2011.11.051
Abstract: Coagulation factor FXI (FXI), a plasma serine protease zymogen, has important roles in both intrinsic and extrinsic coagulation pathways and bridges the initiation and amplification phases o...
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Rong He,
Dong Chen,
Shilin He
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Review article
(In Press Corrected Proof)
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26 December 2011 |
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Diabetes mellitus and thrombosis
DOI: 10.1016/j.thromres.2011.11.052
Abstract: Atherothrombosis is the leading cause of morbidity and mortality in patients with diabetes mellitus. Several mechanisms contribute to the diabetic prothrombotic state, including endothelial ...
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Natale Vazzana,
Paola Ranalli,
Chiara Cuccurullo,
Giovanni Davì
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Review article
(In Press Corrected Proof)
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26 December 2011 |
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Anti-phospholipid antibodies contribute to arteriosclerosis in patients with systemic lupus erythematosus through induction of tissue factor expression and cytokine production from peripheral blood mononuclear cells
DOI: 10.1016/j.thromres.2011.11.048
Abstract: Introduction: In systemic lupus erythematosus (SLE) patients, the prevalence of arteriosclerosis obliterans (ASO) is high despite a lack of common risk factors for ASO. The main objective of...
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Yukari Motoki,
Junzo Nojima,
Masashi Yanagihara,
Hidehiro Tsuneoka,
Tomohiro Matsui,
Misa Yamamoto,
Kiyoshi Ichihara
et al.
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Full-length article
(In Press Corrected Proof)
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23 December 2011 |
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Gender-dependent up-regulation of ADAMTS-13 in mice with obesity and hypercholesterolemia
DOI: 10.1016/j.thromres.2011.11.039
Von Willebrand factor (VWF) is a multimeric glycoprotein that mediates platelet adhesion to subendothelium at sites of vessel injury. It also mediates platelet adhesion to endothelial cells and aggreg...
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Mine Y. Liu,
Zhou Zhou,
Ruidong Ma,
Zhenyin Tao,
Huiwan Choi,
Angela L. Bergeron,
Huaizhu Wu,
Jing-fei Dong
et al.
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Correspondence
(In Press Corrected Proof)
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23 December 2011 |
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The influence of fondaparinux on the diagnosis of postoperative deep vein thrombosis by soluble fibrin and D-dimer
DOI: 10.1016/j.thromres.2011.11.046
Abstract: Introduction: There are many reports concerning the fondaparinux prophylaxis of deep vein thrombosis (DVT) after surgery, but little is known about the usefulness of diagnosing DVT by the th...
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R. Niimi,
M. Hasegawa,
D.Q. Shi,
A. Sudo
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Full-length article
(In Press Corrected Proof)
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23 December 2011 |
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The SISET incorrectly cited the JAAM DIC scoring system
DOI: 10.1016/j.thromres.2011.12.010
We read with interest the recent issue of Thrombosis Research from the Italian Society for Haemostasis and Thrombosis (SISET) about developing guidelines for clinical practice regarding the diagnosis ...
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Satoshi Gando
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Correspondence
(In Press Corrected Proof)
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22 December 2011 |
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Endothelial and platelet function alterations in HIV-infected patients
DOI: 10.1016/j.thromres.2011.11.022
Abstract: The HIV epidemic has huge dimensions: in 2009, 33.3million people worldwide, including 2.5million children, were affected by human immunodeficiency virus (HIV) infection. The introduction of...
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P. Gresele,
E. Falcinelli,
M. Sebastiano,
F. Baldelli
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Review article
(In Press Corrected Proof)
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22 December 2011 |
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Influence of CYP4F2 genotype on warfarin dose requirement–a systematic review and meta-analysis
DOI: 10.1016/j.thromres.2011.11.043
Abstract: Introduction: Warfarin is a commonly used oral anticoagulant and the dosage is individually adjusted on the basis of the international normalized ratio (INR) monitoring. It is well known tha...
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Ruijuan Liang,
Chunling Wang,
Hong Zhao,
Jie Huang,
Dayi Hu,
Yihong Sun
et al.
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Full-length article
(In Press Corrected Proof)
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22 December 2011 |
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Myeloid cell tissue factor does not contribute to venous thrombogenesis in an electrolytic injury model
DOI: 10.1016/j.thromres.2011.11.027
Abstract: Introduction: Tissue factor (TF) is a potent initiator of the extrinsic coagulation cascade. The role and source of TF in venous thrombotic disease is not clearly defined. Our study objectiv...
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Anna L. Hampton,
Jose A. Diaz,
Angela E. Hawley,
Shirley K. Wrobleski,
Jian-Guo Wang,
Rebecca D. Lee,
Daniel Kirchhofer,
Robert E. Sigler,
Thomas W. Wakefield,
Nigel Mackman,
Daniel D. Myers
et al.
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Full-length article
(In Press Corrected Proof)
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22 December 2011 |