Thirty-day mortality rate in women with cancer and venous thromboembolism. Findings from the RIETE Registry

Trujillo-Santos, Javier; Casa, José Manuel; Casado, Ignacio; Samperiz, Ángel Luis; Quintavalla, Roberto; Sahuquillo, Joan Carles; Monreal, Manuel; the RIETE Investigators,

doi:10.1016/S0049-3848(11)00006-5

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Volume 127, Supplement 3 , Pages S1-S4, February 2011

Thirty-day mortality rate in women with cancer and venous thromboembolism. Findings from the RIETE Registry

Javier Trujillo-Santos
- Department of Internal Medicine, Hospital Universitario Santa María de Rosell, Cartagena, Spain
José Manuel Casa
- Department of Internal Medicine, Hospital Infanta Cristina, Parla, Spain
Ignacio Casado
- Department of Pneumonology, Hospital Universitario Virgen de las Nieves, Granada, Spain
Ángel Luis Samperiz
- Department of Internal Medicine, Hospital Reina Sofía, Tudela, Spain
Roberto Quintavalla
- Department of Internal Medicine, Azienda Ospedaliera Universitaria, Parma, Italy
Joan Carles Sahuquillo
- Department of Internal Medicine, Hospital Municipal, Badalona, Spain
Manuel Monreal
- Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
- Corresponding author. Manuel Monreal. Servicio de Medicina Interna. Hospital Universitari Germans Trias i Pujol. Carretera del Canyet s.n. 08916 Badalona (Barcelona), Spain. Tel.: +34934651200 (ext. 3322); fax: +34934978843
the RIETE Investigators

Abstract

The influence of the site of cancer on outcome in cancer women with venous thromboembolism (VTE) is poorly understood. Reliable information on its influence might facilitate better use of prevention strategies.

We assessed the 30-day outcome in all women with active cancer in the RIETE Registry, trying to identify if differences exist according to the tumor site.

Up to May 2010, 2474 women with cancer and acute VTE had been enrolled. The most common sites were the breast (26%), colon (13%), uterus (9.3%), and haematologic (8.6%) cancers. During the 30-day study period, 329 (13%) patients died. Of them, 71 (2.9%) died of pulmonary embolism (PE), 22 (0.9%) died of bleeding. Fatal PE was more common in women with breast, colorectal, lung or pancreatic cancer (59% of the fatal PEs). Fatal bleeding was more frequent in women with colorectal, haematologic, ovarian cancer or carcinoma of unknown origin (55% of fatal bleedings).

Keywords: Cancer , Venous thromboembolism , Mortality , Women

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