Thrombosis Research
Volume 126, Issue 2 , Pages 103-106 , August 2010

Haemostatic profile of healthy premature small for gestational age neonates

  • George Mitsiakos

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece
    • Corresponding Author InformationCorresponding author. Tel.: +30 2310693354; Fax: +30 2310693360.
    • ,
  • Evaggelia Giougi

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece
    • ,
  • Ilias Chatziioannidis

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece
    • ,
  • Paraskevi Karagianni

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece
    • ,
  • Emmanouil Papadakis

      Affiliations

    • Hematology Department, G.P.N. Papageorgiou, Thessaloniki, Greece
    • ,
  • Christos Tsakalidis

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece
    • ,
  • Georgia Papaioannou

      Affiliations

    • Hematology Department, G.P.N. Papageorgiou, Thessaloniki, Greece
    • ,
  • Pavlos Malindretos

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece
    • ,
  • Nikolaos Nikolaidis

      Affiliations

    • 2nd NICU and Νeonatology Department of Aristotle University of Thessaloniki, G.P.N. Papageorgiou, Ring Road Nea Efkarpia, T.K. 56403 Thessaloniki, Greece

Received 9 September 2009 ,Revised 1 May 2010 ,Accepted 13 May 2010.

References 

  1. McIntire DD, Bloom SL, Casey BM, Leveno KJ. Birth weight in relation to morbidity and mortality among newborn infants. N Engl J Med. 1999;340:1234–1238
  2. Regev RH, Lusky A, Dolfin T, Litmanovitz I, Arnon S, Reichman B. Israel Neonatal Network. Excess mortality and morbidity among small-for-gestational-age premature infants: a population based study. J Pediatr. 2003;143:186–191
  3. Bernstein IM, Horbar JD, Badger GJ, Ohlsson A, Golan A. Morbidity and mortality among very-low-birth-weight neonates with intrauterine growth restriction: the Vermont Oxford Network. Am J Obstet Gynecol. 2000;182:198–206
  4. Aucott SW, Donohue PK, Northington FJ. Increased morbidity in severe early intrauterine growth restriction. J Perinatol. 2004;24:435–440
  5. Tommiska V, Heinonen K, Lehtonen L, Renlund M, Saarela T, Tammela O, et al. No improvement in outcome of nationwide extremely low birthweight infant populations between 1996-7 and 1999-2000. Pediatrics. 2007;119:29–36
  6. Andrew Maureen E, Monagle Paul, deVeber Gabrielle, Chan Anthony KC. Thromboembolic Disease and Antithrombotic Therapy in Newborns. Hematology. 2001;358–374
  7. Williams MD, Chalmers EA, Gibson BE. The investigation and management of neonatal haemostasis and thrombosis. Br J Haematol. 2002;119(2):295–309
  8. Rosenberg A. The IUGR newborn. Semin Perinatol. 2008;32(3):219–224
  9. Peters M, ten Cate JW, Koo LH, Breederveld C. Persistent antithrombin III deficiency: risk factor for thromboembolic complications in neonates small for gestational age. J Pediatr. 1984;105(2):310–314
  10. Salonvaara M, Riikonen P, Kekomaki R, Vahtera E, Mahlamaki E, Halonen P, et al. Effects of gestational age and prenatal and perinatal events on the coagulation status in premature infants. Arch Dis Child Fetal Neonatal Ed. 2003;88(4):F319–F323
  11. Wu Yvonne W, March Whitney M, Croen Lisa A, Grether Judith K, Escobar Gabriel J, Newman Thomas B. Perinatal Stroke in Children With Motor Impairment: A Population-Based Study. Pediatrics. 2004;114:612–619
  12. Chalmers EA. Neonatal coagulation problems. Arch Dis Child Fetal Neonatal Ed. 2004;89:475–478
  13. Manco-Johnson MJ. Development of hemostasis in the fetus. Thromb Res. 2005;115(Sl1):55–63
  14. Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, et al. Development of the human coagulation system in the full-term infant. Blood. 1987;70(1):165–172
  15. Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, et al. Development of the human coagulation system in the healthy premature infant. Blood. 1988;72(5):1651–1657
  16. Monagle P, Barnes Ch, Ignjatovic V, Furmedge J, Newall F, Chan A, et al. Developmental Haemostasis: Impact for clinical haemostasis laboratories. Thromb Haemost. 2006;95:362–372
  17. Cerneca F, de Vonderweid U, Simeone R, Forleo V. The importance of hematocrit in the interpretation of coagulation tests in the full-term newborn infant. Haematologica. 1994;79(1):25–28
  18. Reverdiau-Moalic P, Delahousse B, Body G, Bardos P, Leroy J, Gruel Y. Evolution of blood coagulation activators and inhibitors in the healthy human fetus. Blood. 1996;88(3):900–906
  19. Mitsiakos G, Papaioannou G, Papadakis E, Chatziioannidis E, Giougi E, Karagianni P, et al. Haemostatic profile of full-term, healthy, small for gestational age neonates. Thromb Res. 2009;124(3):288–291
  20. Hathaway W, Corrigan J. Report of Scientific and Standardization Subcommittee on Neonatal Haemostasis. Normal coagulation data for fetuses and newborn infants. Thromb Haemost. 1991;65:323–325
  21. Monagle P, Ignjatovic V, Savoia H. Hemostasis in neonates and children: Pitfalls and dilemmas. Blood Rev. 2010;24:63–68
  22. Greg Alexander R, Michael Kogan D, John Himes H. 1994–1996 U.S. Singleton Birth Weight Percentiles for Gestational Age by Race, Hispanic Origin, and Gender. Matern Child Health J. 1999;3(4):225–231
  23. Thornburg C, Pipe S. Neonatal thromboembolic emergencies. Semin Fetal Neonatal Med. 2006;11:198–206
  24. Langdell RD, Wagner RH, Brinkhous KM. Effect of antihemophilic factor on one-stage clotting tests. J Lab Clin Med. 1953;41:637–647
  25. Larrieu MJ, Weilland C. Utilisation de la “céphaline” dans les tests. Nouv Rev Fr Hématol. 1957;12:199–210
  26. Shearer MJ, Crampton OE, McCarthy PT, Mattock MB. Vitamin K1 in plasma: relationship to vitamin K status, age, pregnancy, diet and disease. Haemostasis. 1986;16(5):83
  27. Puckett RM, Offringa M. Prophylactic vitamin K for vitamin K deficiency bleeding in neonates. Cochrane Database Syst Rev. 2000;CD002776
  28. Mc Donald MM, Johnson ML, Rumack CM, Koops BL, Guggenheim MA, Babb C, et al. Role of coagulopathy in newborn intracranial hemorrhage. Pediatrics. 1984;74:26–31
  29. American Academy of Pediatrics . Committee on Fetus and Newborn Controversies concerning Vitamin K and the newborn. Pediatrics. 2003;112:191–192
  30. Koster T, Blann AD, Briët E, Vandenbroucke JP, Rosendaal FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep- vein thrombosis. Lancet. 1995;345:152–155
  31. Penick GD, Dejanov II, Roberts HR, Webster WP. Elevation of factor VIII in hypercoagulable states. Thromb Diath Haemorrh. 1966;39–48(SV)
  32. Cumming AM, Tait RC, Fildes S, Yoong A, Keeney S, Hay CR. Development of resistance to activated protein C during pregnancy. Br J Haematol. 1995;90:725–727
  33. Clark P, Sattar N, Walker ID, Greer IA. The Glasgow outcome, APCR and Lipid (GOAL) pregnancy study: significance of pregnancy associated activated protein. Thromb Haemost. 2001;85:30–35
  34. Wu KK, Thiagarajan P. Role of endothelium in thrombosis and hemostasis. Annu Rev Med. 1996;47:315
  35. Lijnen HR, Collen D. Endothelium in hemostasis and thrombosis. Prog Cardiovasc Dis. 1997;39:343
  36. Sprengers ED, Kluft C. Plasminogen activator inhibitors. Blood. 1987;69:381
  37. Verstraete M, Su CAPF, Tanswell P, Feuerer W, Collen D. Pharmacokinetics and effects of fibrinolytic and coagulation parameters of two doses of recombinant tissue-type plasminogen activator in healthy volunteers. Thromb Haemost. 1986;56

PII: S0049-3848(10)00293-8

doi: 10.1016/j.thromres.2010.05.010

Thrombosis Research
Volume 126, Issue 2 , Pages 103-106 , August 2010

Article Tools