Thrombosis Research
Volume 125 , Pages S67-S69 , April 2010

Tissue factor microparticles and haemophilia

  • Peter L. Gross

      Affiliations

    • Corresponding Author InformationCorresponding author. Thrombosis and Atherosclerosis Research Institute, 237 Barton Street East, Hamilton, Ontario, Canada L8L 2X2. Tel.: +1 905 521 2100x40779; fax: +1 905 575 2646.
    • ,
  • Nima Vaezzadeh

References 

  1. Davie EW, Ratnoff OD. Waterfall sequence for intrinsic blood clotting. Science. 1964;145:1310–1312
  2. van't Veer C, Mann KG. Regulation of tissue factor initiated thrombin generation by the stoichiometric inhibitors tissue factor pathway inhibitor, antithrombin-III, and heparin cofactor-II. J Biol Chem. 1997;272:4367–4377
  3. Hoffman M, Monroe DM. The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis. Dis Mon. 2003;49:14–21
  4. Falati S, Liu Q, Gross P, Merrill-Skoloff G, Chou J, Vandendries E, et al. Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med. 2003;197:1585–1598
  5. Del Conde I, Shrimpton CN, Thiagarajan P, Lopez JA. Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood. 2005;106:1604–1611
  6. Cawthern KM, van ' V. , Lock JB, DiLorenzo ME, Branda RF, Mann KG. Blood coagulation in hemophilia A and hemophilia C. Blood. 1998;91:4581–4592
  7. Day SM, Reeve JL, Pedersen B, Farris DM, Myers DD, Im M, et al. Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood. 2005;105:192–198
  8. Wang L, Miller C, Swarthout RF, Rao M, Mackman N, Taubman MB. Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury. Blood. 2009;113:705–713
  9. Censarek P, Bobbe A, Grandoch M, Schror K, Weber AA. Alternatively spliced human tissue factor (asHTF) is not pro-coagulant. Thromb Haemost. 2007;97:11–14
  10. McEver RP. Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation. Thromb Haemost. 2001;86:746–756
  11. Falati S, Gross P, Merrill-Skoloff G, Furie BC, Furie B. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nat Med. 2002;8:1175–1181
  12. Chou J, Mackman N, Merrill-Skoloff G, Pedersen B, Furie BC, Furie B. Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood. 2004;104:3190–3197
  13. Chen V, Merrill-Skoloff G, Wang L, Chen S, Mackman N, Furie BC, et al. Intravascular but not extravascular tissue factor is required for fibrin generation during thrombus formation in cremaster arterioles in living mice subjected to laser injury. Blood. 20-12-2009;114(22):140–141[Ref Type: Abstract]
  14. Gross PL, Furie BC, Merrill-Skoloff G, Chou J, Furie B. Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development. J Leukoc Biol. 2005;78:1318–1326
  15. Rauch U, Bonderman D, Bohrmann B, Badimon JJ, Himber J, Riederer MA, et al. Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. Blood. 2000;96:170–175
  16. Hrachovinova I, Cambien B, Hafezi-Moghadam A, Kappelmayer J, Camphausen RT, Widom A, et al. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat Med. 2003;9:1020–1025
  17. Freyssinet JM. Cellular microparticles: what are they bad or good for?. J Thromb Haemost. 2003;1:1655–1662
  18. Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, et al. Differential stimulation of monocytic cells results in distinct populations of microparticles. J Thromb Haemost. 2009;7:1019–1028
  19. Del Conde I, Shrimpton CN, Thiagarajan P, Lopez JA. Tissue factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood. 2005;106:1604–1611
  20. Warkentin TE. Heparin-induced thrombocytopenia: IgG-mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-induced thrombocytopenia. Transfus Med Rev. 1996;10:249–258
  21. Ahn YS. Cell-derived microparticles: 'Miniature envoys with many faces'. J Thromb Haemost. 2005;3:884–887
  22. Enjeti AK, Lincz LF, Seldon M. Microparticles in health and disease. Semin Thromb Hemost. 2008;34:683–691
  23. Trappenburg MC, van Schilfgaarde M, Marchetti M, Spronk HM, ten Cate H, Leyte A, et al. Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia. Haematologica. 2009;94:911–918
  24. Burnier L, Fontana P, Kwak BR, Angelillo-Scherrer A. Cell-derived microparticles in haemostasis and vascular medicine. Thromb Haemost. 2009;101:439–451
  25. Zwicker JI, Liebman HA, Neuberg D, Lacroix R, Bauer KA, Furie BC, et al. Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res. 2009;15:6830–6840
  26. Butenas S, Orfeo T, Mann KG. Tissue factor in coagulation: Which? Where? When?. Arterioscler Thromb Vasc Biol. 2009;29:1989–1996
  27. Abid Hussein MN, Nieuwland R, Hau CM, Evers LM, Meesters EW, Sturk A. Cell-derived microparticles contain caspase 3 in vitro and in vivo. J Thromb Haemost. 2005;3:888–896
  28. Yuana Y, Oosterkamp TH, Bahatyrova S, Ashcroft B, Garcia RP, Bertina RM, et al. Atomic force microscopy: a novel approach to detect nanosized blood microparticles. J Thromb Haemos. 2009;[Epub ahead of print October 19, 2009]
  29. Akram A, Teitel JM, Freedman J, Gross PL. Hemostasis in factor VIII deficient mice is improved after the infusion of monocyte-derived microparticles. J Thromb Haemost. 2007;5:[Ref Type: Abstract]

PII: S0049-3848(10)00094-0

doi: 10.1016/j.thromres.2010.01.041

Thrombosis Research
Volume 125 , Pages S67-S69 , April 2010

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