Thrombosis Research
Volume 126, Issue 2 , Pages 88-92 , August 2010

Use of the Delphi method to facilitate antithrombotics prescription during pregnancy

  • Celine Chauleur

      Affiliations

    • Gynaecology-Obstetrics Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • Clinical Pharmacology Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • Corresponding Author InformationCorresponding author. Gynaecology-Obstetrics Department, Hospital of Saint-Etienne North Hospital, Avenue Albert Raimond, 42270 Saint Priest en Jarez, France. Tel.: +33 4 77 82 86 11; fax: +33 4 77 82 89 54.
    • ,
  • Jean Christophe Gris

      Affiliations

    • Haematology Laboratory, Centre of biological exploration of vessels, thromboses and haemostasis, University Hospital, Caremeau group, Place du Pr. Robert Debré, 30029 Nîmes Cedex 9, EA 2992 "Dynamic of cardiovascular incoherencies", France
    • ,
  • Sylvie Laporte

      Affiliations

    • Clinical Pharmacology Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • ,
  • Florence Rancon

      Affiliations

    • Clinical Pharmacology Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • ,
  • Marie-Noëlle Varlet

      Affiliations

    • Gynaecology-Obstetrics Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • ,
  • Herve Decousus

      Affiliations

    • Clinical Pharmacology Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • ,
  • Patrick Mismetti

      Affiliations

    • Clinical Pharmacology Department, EA3065 (Thrombosis Research Group), University Hospital, 42055 Saint-Etienne Cedex 2, Jean Monnet University, France
    • ,
  • STRATHEGE Group

Received 6 July 2009 ,Revised 22 October 2009 ,Accepted 17 January 2010.

References 

  1. Conférence de consensus. In: Thrombophilie et grossesse ANAES. 2003;p. 1–7
  2. Bates SM, Greer IA, Hirsh J, Ginsberg JS. Use of antithrombotic agents during pregnancy: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126:627S–644S
  3. Bates SM, Greer IA, Pabinger I, Sofaer S, Hirsh J American College of Chest Physicians. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:844S–886S
  4. Chauleur C, Vieira C, Seffert P. Prophylaxis of thromboembolic disease in obstetrics after the French guidelines publication. Gynecol Obstet Fertil. 2008;36:23–34
  5. Graham B, Regehr G, Wright JG. Delphi as a method to establish consensus for diagnostic criteria. J Clin Epidemiol. 2003;56:1150–1156
  6. Kahan JP, Bernstein SJ, Leape LL, Hilborne LH, Park RE, Parker L, et al. Measuring the necessity of medical procedures. Med Care. 1994;32:357–365
  7. Brook RH, Chassin MR, Fink A, Solomon DH, Kosecoff J, Park RE. A method for the detailed assessment of the appropriateness of medical technologies. Int J Technol Assess Health Care. 1986;2:53–63
  8. Lindeman CA. Delphi survey of priorities in clinical nursing research. Nurs Res. 1975;24:434–441
  9. Murphy MK, Black NA, Lamping DL, McKee CM, Sanderson CF, Askham J, et al. Consensus development methods, and their use in clinical guideline development. Health Technol Assess. 1998;2:i-v, 1
  10. Jairath N, Weinstein J. The Delphi methodology (Part Two): A useful administrative approach. Can J Nurs Adm. 1994;7:7–20
  11. Jairath N, Weinstein J. The Delphi methodology (Part one): A useful administrative approach. Can J Nurs Adm. 1994;7:29–42
  12. Jones J, Hunter D. Consensus methods for medical and health services research. BMJ. 1995;311:376–380
  13. Dalkey N, Helmer O. Delphi Technique: characteristics and sequence model to the use of experts. Manag Sci. 1963;3:458–4679 pp.
  14. Bourrée F, Michel P, Salmi LR. Consensus methods: review of original methods and their main alternatives used in public health. Rev Epidemiol Sante Publique. 2008;56:415–423
  15. Wu O, Robertson L, Twaddle S, Lowe GDO, Clark P, Greaves M, et al. Screening for thrombophilia in high-risk situations: systematic review and cost-effectiveness analysis. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study. Health Technol Assess. 2006;10:1–10
  16. Lissalde-Lavigne G, Fabbro-Peray P, Cochery-Nouvellon E, Mercier E, Ripart-Neveu S, Balducchi JP, et al. Factor V Leiden and prothrombin G20210A polymorphisms as risk factors for miscarriage during a first intended pregnancy: the matched case-control 'NOHA first' study. J Thromb Haemost. 2005;3:2178–2184
  17. Eldor A. The use of low-molecular-weight heparin for the management of venous thromboembolism in pregnancy. Eur J Obstet Gynecol Reprod Biol. 2002;104:3–13
  18. Ray JG, Chan WS. Deep vein thrombosis during pregnancy and the puerperium: a meta-analysis of the period of risk and the leg of presentation. Obstet Gynecol Surv. 1999;54:265–271
  19. Pabinger I, Grafenhofer H, Kaider A, Kyrle PA, Quehenberger P, Mannhalter C, et al. Risk of pregnancy-associated recurrent venous thromboembolism in women with a history of venous thrombosis. J Thromb Haemost. 2005;3:949–954
  20. Stephano V, Rossi E, Za T, Leone G. De Prophylaxis and treatment of venous thromboembolism in individuals with inherited thrombophilia. Semin Thromb Hemost. 2006;32:767–780
  21. Bonnar J. Can more be done in obstetric and gynecologic practice to reduce morbidity and mortality associated with venous thromboembolism?. Am J Obstet Gynecol. 1999;180:784–791
  22. Danilenko-Dixon DR, Heit JA, Silverstein MD, Yawn BP, Petterson TM, Lohse CM, et al. Risk factors for deep vein thrombosis and pulmonary embolism during pregnancy or post partum: a population-based, case-control study. Am J Obstet Gynecol. 2001;184:104–110
  23. Greer IA. Prevention of venous thromboembolism in pregnancy. Baillieres Best Pract Res Clin Haematol. 2003;16:261–278
  24. McColl MD, Walker ID, Greer IA. The role of inherited thrombophilia in venous thromboembolism associated with pregnancy. Br J Obstet Gynaecol. 1999;106:756–766
  25. Ginsberg JS, Greer I, Hirsh J. Use of antithrombotic agents during pregnancy. Chest. 2001;119:122S–131S
  26. James AH. Prevention and management of venous thromboembolism in pregnancy. Am J Med. 2007;120:S26–S34
  27. Sanson BJ, Lensing AW, Prins MH, Ginsberg JS, Barkagan ZS, Lavenne-Pardonge E, et al. Safety of low-molecular-weight heparin in pregnancy: a systematic review. Thromb Haemost. 1999;81:668–672
  28. Ensom MH, Stephenson MD. Low-molecular-weight heparins in pregnancy. Pharmacotherapy. 1999;19:1013–1025
  29. Zotz RB, Gerhardt A, Scharf RE. Prediction, prevention, and treatment of venous thromboembolic disease in pregnancy. Semin Thromb Hemost. 2003;29:143–154
  30. Gibson PS, Rosene-Montella K. Drugs in pregnancy. Anticoagulants. Baillieres Best Pract Res Clin Obstet Gynaecol. 2001;15:847–861
  31. Ellison J, Walker ID, Greer IA. Antenatal use of enoxaparin for prevention and treatment of thromboembolism in pregnancy. BJOG. 2000;107:1116–1121
  32. Laurent P, Dussarat GV, Bonal J, Jego C, Talard P, Bouchiat C, et al. Low molecular weight heparins: a guide to their optimum use in pregnancy. Drugs. 2002;62:463–477
  33. De Stefano V, Martinelli I, Rossi E, Battaglioli T, Za T, Mannuccio Mannucci P, et al. The risk of recurrent venous thromboembolism in pregnancy and puerperium without antithrombotic prophylaxis. Br J Haematol. 2006;135:386–391
  34. James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol. 2006;194:1311–1315
  35. Gerhardt A, Scharf RE, Zotz RB. Effect of hemostatic risk factors on the individual probability of thrombosis during pregnancy and the puerperium. Thromb Haemost. 2003;90:77–85
  36. Kujovich JL. Thrombophilia and pregnancy complications. Am J Obstet Gynecol. 2004;191:412–424
  37. Paidas MJ, Ku DHW, Langhoff-Roos J, Arkel YS. Inherited thrombophilias and adverse pregnancy outcome: screening and management. Semin Perinatol. 2005;29:150–163
  38. Preston FE, Rosendaal FR, Walker ID, Briët E, Berntorp E, Conard J, et al. Increased fetal loss in women with heritable thrombophilia. Lancet. 1996;348:913–916
  39. Chauleur C, Quenet S, Varlet MN, Seffert P, Laporte S, Decousus H, et al. Feasibility of an easy-to-use risk score in the prevention of venous thromboembolism and placental vascular complications in pregnant women: a prospective cohort of 2736 women. Thromb Res. 2008;122:478–484
  40. Bauersachs RM, Dudenhausen J, Faridi A, Fischer T, Fung S, Geisen U, et al. Risk stratification and heparin prophylaxis to prevent venous thromboembolism in pregnant women. Thromb Haemost. 2007;98:1237–1245
  41. Dargaud Y, Rugeri L, Ninet J, Negrier C, Trzeciak MC. Management of pregnant women with increased risk of venous thrombosis. Int J Gynaecol Obstet. 2005;90:203–207
  42. Weiss N, Bernstein PS. Risk factor scoring for predicting venous thromboembolism in obstetric patients. Am J Obstet Gynecol. 2000;182:1073–1075
  43. Lindqvist PG, Kublikas M, Dahlbäck B. Individual risk assessment of thrombosis in pregnancy. Acta Obstet Gynecol Scand. 2002;81:412–416
  44. Jacobsen AF, Skjeldestad FE, Sandset PM. Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study. J Thromb Haemost. 2008;6:905–912
  45. Pabinger I, Grafenhofer H, Kaider A, Ilic A, Eichinger S, Quehenberger P, et al. Preeclampsia and fetal loss in women with a history of venous thromboembolism. Arterioscler Thromb Vasc Biol. 2001;21:874–879

PII: S0049-3848(10)00040-X

doi: 10.1016/j.thromres.2010.01.012

Thrombosis Research
Volume 126, Issue 2 , Pages 88-92 , August 2010

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