Thrombosis Research
Volume 125, Issue 5 , Pages e206-e209 , May 2010

Combined use of D-dimer and P-selectin for the diagnosis of splenic or portal vein thrombosis following splenectomy

  • Li Wang

      Affiliations

    • Department of General Surgery, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng 252000, Shandong Province, China
    • ,
  • Gui-Jie Liu

      Affiliations

    • Department of General Surgery, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng 252000, Shandong Province, China
    • Corresponding Author InformationCorresponding authors. Wang is to be contacted at School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW 2678, Australia. Tel.: +61 2 69332905; fax: +61 2 69 332587.
    • ,
  • Yan-Xin Chen

      Affiliations

    • Department of General Surgery, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng 252000, Shandong Province, China
    • ,
  • Huai-Ping Dong

      Affiliations

    • Department of General Surgery, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng 252000, Shandong Province, China
    • ,
  • Yan-Qiang Zhang

      Affiliations

    • Department of General Surgery, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng 252000, Shandong Province, China
    • ,
  • Le-Xin Wang

      Affiliations

    • School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW 2650, Australia
    • Corresponding Author InformationCorresponding authors. Wang is to be contacted at School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW 2678, Australia. Tel.: +61 2 69332905; fax: +61 2 69 332587.

Received 21 October 2009 ,Revised 11 December 2009 ,Accepted 26 December 2009.

References 

  1. Krauth MT, Lechner K, Neugebauer EA, Pabinger I. The postoperative splenic/portal vein thrombosis after splenectomy and its prevention–an unresolved issue. Haematol. 2008;93:1227–1232
  2. Kearon C, Julian JA, Newman TE, Ginsberg JS. Noninvasive diagnosis of deep venous thrombosis. McMaster Diagnostic Imaging Practice Guidelines Initiative. Ann Intern Med. 1998;128:663–677
  3. Stein PD, Hull RD, Patel KC, Olson RE, Ghali WA, Brant R, et al. D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review. Ann Intern Med. 2004;140:589–602
  4. Fancher TL, White RH, Kravitz RL. Combined use of rapid D-dimer testing and estimation of clinical probability in the diagnosis of deep vein thrombosis: systematic review. BMJ. 2004;20:329:821
  5. Stamou KM, Toutouzas KG, Kekis PB, Nakos S, Gafou A, Manouras A, et al. Prospective study of the incidence and risk factors of postsplenectomy thrombosis of the portal, mesenteric, and splenic veins. Arch Surg. 2006;141:663–669
  6. Blann AD, Nadar SK, Lip GY. The adhesion molecule P-selectin and cardiovascular disease. Eur Heart J. 2003;24:2166–2179
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  8. Ay C, Simanek R, Vormittag R, Dunkler D, Alguel G, Koder S, et al. High plasma levels of soluble P-selectin are predictive of venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS). Blood. 2008;112:2703–2708
  9. Kyrle PA, Hron G, Eichinger S, Wagner O. Circulating P-selectin and the risk of recurrent venous thromboembolism. Thromb Haemost. 2007;97:880–883
  10. Orozco H, Mercado MA, Chan C, Ramos-Gallard G, Gálvez-Treviño R, Salgado-Nesme N, et al. Current role of surgery for the treatment of portal hypertension. Ann Hepatol. 2002;1:175–178
  11. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60:646–649
  12. Gurbel PA, Kereiakes DJ, Dalesandro MR, Bahr RD, O'Connor CM, Serebruany VL. Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department. Am Heart J. 2000;139:320–328
  13. Hidajat N, Stobbe H, Griesshaber V, Schroder RJ, Felix R. Portal vein thrombosis: etiology, diagnostic strategy, therapy and management. Vasa. 2005;34:81–92
  14. Winslow ER, Brunt LM, Drebin JA, Soper NJ, Klingensmith ME. Portal vein thrombosis after splentectomy. Am J Surg. 2002;184:631–635
  15. Webster GJ, Burroughs AK, Riordan SM. Review article. Portal vein thrombosis - new insights into aetiology and management. Aliment Pharmacol Ther. 2005;21:1–9
  16. Ikeda M, Sekimoto M, Takiguchi S, Kubota M, Ikenaga M, Yamamoto H, et al. High incidence of thrombosis of the portal venous system after laparoscopic splenectomy: a prospective study with contrast-enhanced CT scan. Ann Surg. 2005;241:208–216

PII: S0049-3848(09)00565-9

doi: 10.1016/j.thromres.2009.12.012

Thrombosis Research
Volume 125, Issue 5 , Pages e206-e209 , May 2010

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