« Previous
Next »
Thrombosis Research
Volume 125, Issue 3
, Pages 257-261
, March 2010
PAR1 antagonist mediated antithrombotic activity in extracorporeal arterio-venous shunt in the rat
References
- . Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64:1057–1068
- . Protease-activated receptors: contribution to physiology and disease. Physiol Rev. 2004;84:579–621
- . Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest. 1999;103:879–887
- . Thrombin signalling and protease-activated receptors. Nature. 2000;407:258–264
- . Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood. 1993;82:103–106
- . Species differences in platelet responses to thrombin and SFLLRN receptor-mediated calcium mobilization and aggregation, and regulation by protein kinases. Thromb Res. 1995;78:505–519
- Protease-activated receptor 3 is a second thrombin receptor in humans. Nature. 1997;386:502–506
- Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis. Circulation. 2006;113:1244–1254
- Selective inhibition of protease-activated receptor 4-dependent platelet activation by YD-3. Thromb Haemost. 2002;87:1026–1033
- . Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist. Biochem Pharmacol. 2000;60:1425–1434
- . Nonpeptide thrombin receptor antagonists. Drugs Future. 2001;26:1065–1085
- . Thrombin receptor (PAR-1) antagonists as novel antithrombotic agents. Expert Opin Ther Patents. 2006;16:493–505
- . Differential involvement of serotonin 2A/C and thromboxane A2/prostanoid receptors in high- vs. low-shear rate arterial thrombosis in rabbits. J Pharmacol Exp Ther. 1997;280:761–769
- . Prolongation of bleeding time by acute hemolysis in rats: a role for nitric oxide. Am J Physiol. 1997;272:H2875–H2884
- . The rat as an experimental animal. Science. 1989;245:269–276
- . Examination of the utility of the rat as an animal model for human anticoagulation. Haemostasis. 1987;17:206–210
- . Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report-Subcommittee on rheology of the international committee on thrombosis and haemostasis. Thromb Haemost. 1986;55:415–435
- . Expression of the platelet procoagulant activity in vivo in thrombus formation in an extracorporeal shunt in the rat. Thromb Res. 1984;36:223–232
- . Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin. Am J Pathol. 1994;144:975–985
- The indazole derivative YD-3 inhibits thrombin-induced vascular smooth muscle cell proliferation and attenuates intimal thickening after balloon injury. Thromb Haemost. 2004;92:1232–1239
PII: S0049-3848(09)00219-9
doi: 10.1016/j.thromres.2009.05.004
© 2009 Elsevier Ltd. All rights reserved.
« Previous
Next »
Thrombosis Research
Volume 125, Issue 3
, Pages 257-261
, March 2010
