« Previous
Next »
Thrombosis Research
Volume 124, Issue 4
, Pages 403-408
, September 2009
Prognostic value of pre-surgical plasma PAI-1 (plasminogen activator inhibitor-1) levels in breast cancer
References
- . The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer. 1997;72:1–22
- . Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease. Thromb Haemost. 2005;93:631–640
- Urokinase-type plasminogen activator and its inhibitor type 1 predict disease outcome and therapy response in primary breast cancer. Clin Breast Cancer. 2004;5:348–352
- Urokinase-type plasminogen activator (uPA) and its inhibitor PAI-I: novel tumor-derived factors with a high prognostic and predictive impact in breast cancer. Thromb Haemost. 2004;91:450–456
- Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst. 2002;94:116–128
- Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1. J Natl Cancer Inst. 2001;93:913–920
- Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424). Cancer Res. 2002;62:4617–4622
- Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression. Cancer Epidemiol Biomark Prev. 2006;15:2107–2114
- Plasminogen activator inhibitor-1 4G/5G polymorphism in breast cancer patients and its association with tissue PAI-1 levels and tumor severity. Thromb Res. 2006;117:487–492
- Markers of the uPA System and Common Prognostic Factors in Breast Cancer. Am J Clin Pathol. 2007;128:112–117
- . Functional plasminogen activator inhibitor-1 gene variants and breast cancer survival. Clin Cancer Res. 2006;12:6037–6042
- PAI-1 -675 4G/5G polymorphism as a prognostic biomarker in breast cancer. Breast Cancer Res Treat. 2008;109:165–175
- . Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism is not associated with breast cancer. Acta Biochim Pol. 2000;47:191–199
- . Mutations in mismatch repair genes are involved in the neoplastic transformation of human breast epithelial cells. Int J Oncol. 2003;23:411–419
- . Longitudinal stability of coagulation, fibrinolysis, and inflammation factors in stored plasma samples. Thromb Haemost. 2001;86:1495–1500
- . SNPStats: a web tool for the analysis of association studies. Bioinformatics. 2006;22:1928–1929
- Physiological and pathological changes of plasma urokinase-type plasminogen activator, plasminogen activator inhibitor-1, and urokinase-type plasminogen activator receptor levels in healthy females and breast cancer patients. Breast Cancer Res Treat. 1998;49:41–50
- . Increased soluble P-selectin in patients with haematological and breast cancer: a comparison with fibrinogen, plasminogen activator inhibitor and von Willebrand factor. Blood Coagul Fibrinolysis. 2001;12:43–50
- Measurement of plasminogen activator system components in plasma and tumor tissue extracts obtained from patients with breast cancer: an EORTC Receptor and Biomarker Group collaboration. Oncol Rep. 2005;14:235–239
- Validation of blood collection procedures for the determination of circulating vascular endothelial growth factor (VEGF) in different blood compartments. Int J Biol Markers. 2001;16:87–96
- . PAI-1 promoter polymorphism modulates uPA-PAI complex accumulation by breast cancer cells. Oncology. 2002;62:286–290
- . Plasminogen activator inhibitor -1 gene 4G/5G polymorphism in patients with breast cancer. J BUON. 2006;11:481–484
- . Polymorphisms of short tandem repeat of genes and breast cancer susceptibility. Eur J Surg Oncol. 2007;33:529–534
- . Allelic variation of BAT-25 and BAT-26 mononucleotide repeat loci in tumours from a group of young women with breast cancer. Int J Oncol. 2004;25:771–775
- . Inflammation and cancer. Nature. 2002;420:860–867
☆ Presented at the 4th International Conference on Thrombosis and Hemostasis Issues in Cancer (ICTHIC), Bergamo, 26-28 October, 2007.
PII: S0049-3848(09)00128-5
doi: 10.1016/j.thromres.2009.02.014
© 2009 Elsevier Ltd. All rights reserved.
« Previous
Next »
Thrombosis Research
Volume 124, Issue 4
, Pages 403-408
, September 2009
