Thrombosis Research
Volume 122 , Pages S20-S26 , 2008

Development of catheter-directed intrathrombus thrombolysis with plasmin for the treatment of acute lower extremity arterial occlusion

References 

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  2. McNamara TO, Fischer JR. Thrombolysis of peripheral arterial and graft occlusions: improved results using high-dose urokinase. AJR Am J Roentgenol. 1985;144:769–775
  3. Ouriel K, Shortell CK, Azodo MV, Guiterrez OH, Marder VJ. Acute peripheral arterial occlusion: predictors of success in catheter-directed thrombolytic therapy. Radiology. 1994;193:561–566
  4. Gardiner GA, Harrington DP, Koltun W, Whittemore A, Mannick JA, Levin DC. Salvage of occluded arterial bypass grafts by means of thrombolysis. J Vasc Surg. 1989;9:426–431
  5. McNamara TO, Bomberger RA. Factors affecting initial and 6 month patency rates after intraarterial thrombolysis with high dose urokinase. Am J Surg. 1986;152:709–712
  6. Sullivan KL, Gardiner GA, Shapiro MJ, Bonn J, Levin DC. Acceleration of thrombolysis with a high-dose transthrombus bolus technique. Radiology. 1989;173:805–808
  7. Ward AS, Andaz SK, Bygrave S. Thrombolysis with tissue-plasminogen activator: results with a high-dose transthrombus technique. J Vasc Surg. 1994;19:503–508
  8. Kandarpa K. Technical determinants of success in catheter-directed thrombolysis for peripheral arterial occlusions. J Vasc Interv Radiol. 1995;6:55S–61S
  9. Berridge DC, Gregson RH, Hopkinson BR, Makin GS. Randomized trial of intra-arterial recombinant tissue plasminogen activator, intravenous recombinant tissue plasminogen activator and intra-arterial streptokinase in peripheral arterial thrombolysis. Br J Surg. 1991;78:988–995
  10. Ouriel K, Shortell CK, DeWeese JA, Green RM, Francis CW, Azodo MV, et al A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia. J Vasc Surg. 1994;19:1021–1030
  11. Ouriel K, Veith FJ, Sasahara AA. A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. N Engl J Med. 1998;338:1105–1111
  12. Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity. The STILE trial. Ann Surg. 1994;220:251–266discussion 266–258
  13. Plate G, Jansson I, Forssell C, Weber P, Oredsson S. Thrombolysis for acute lower limb ischaemia-a prospective, randomised, multicentre study comparing two strategies. Eur J Vasc Endovasc Surg. 2006;31:651–660
  14. Ouriel K, Cynamon J, Weaver FA, Dardik H, Akers D, Blebea J, et al. A phase I trial of alfimeprase for peripheral arterial thrombolysis. J Vasc Interv Radiol. 2005;16:1075–1083
  15. Weaver FA, Perler BA, Levy MD, et al. Efficacy and safety of alfimeprase in subjects with acute peripheral arterial occlusion (PAO): the NAPA phase 3 program. Poster presented at: International Society of Endovascular Therapy (ISET); January 18–22, 2008; Hollywood, Fl.
  16. Marder VJ, Landskroner K, Novokhatny V, Zimmerman TP, Kong M, Kanouse JJ, et al. Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit. Thromb Haemost. 2001;86:739–745
  17. Shlansky-Goldberg R, Matsumoto AH, Baumbach GA, Siegel JB, Raabe RD, Murphy TP, et al. A first-in-human phase 1 trial of locally delivered human plasmin for hemodialysis graft occlusion. J Thromb Haemost. 2008;6:944–950

PII: S0049-3848(08)00241-7

doi: 10.1016/j.thromres.2008.06.012

Thrombosis Research
Volume 122 , Pages S20-S26 , 2008

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