Thrombosis Research
Volume 122 , Pages S16-S19 , 2008

Phase 1 study of human plasma-derived plasmin (TAL-05-00018) in hemodialysis graft occlusion

References 

  1. Bookstein JJ, Fellmeth B, Roberts A, et al. Pulsed-spray pharmacomechanical thrombolysis: preliminary clinical results. AJR Am J Roentgenol. 1989;152:1097–1100
  2. Valji K. Transcatheter treatment of thrombosed hemodialysis access grafts. AJR Am J Roentgenol. 1995;164:823–829
  3. Sofocleous CT, Hinrichs CR, Weiss SH, et al. Alteplase for hemodialysis access graft thrombolysis. J Vasc Interv Radiol. 2002;13:775–784
  4. Marder VJ, Stewart D. Towards safer thrombolytic therapy. Semin Hematol. 2002;39:206–216
  5. Marder VJ. The use of thrombolytic agents: choice of patient, drug administration, laboratory monitoring. Ann Intern Med. 1979;90:802–808
  6. Dotter CT, Rösch J, Seaman AJ. Selective clot lysis with low-dose streptokinase. Radiology. 1974;111:31–37
  7. Ouriel K, Gray B, Clair DG, Olin J. Complications associated with the use of urokinase and recombinant tissue plasminogen activator for catheter-directed peripheral arterial and venous thrombolysis. J Vasc Interv Radiol. 2000;11:295–298
  8. Henkin J, Marcotte P, Yang HC. The plasminogen-plasmin system. Prog Cardiovasc Dis. 1991;34:135–164
  9. Wiman B, Lijnen HR, Collen D. On the specific interaction between the lysine-binding sites in plasmin and complementary sites in alpha2-antiplasmin and in fibrinogen. Biochim Biophys Acta. 1979;579:142–154
  10. Collen D. On the regulation and control of fibrinolysis. Thromb Haemost. 1980;43:77–89
  11. Middlebrook MR, Amygdalos MA, Soulen MC, et al. Thrombosed hemodialysis grafts: percutaneous mechanical balloon declotting versus thrombolysis. Radiology. 1995;196:73–77
  12. R.D. Shlansky-Goldberg, A.H. Matsumoto, G.A. Baumbach, et al. A first-in-human phase 1 trial of locally-delivered human plasmin for hemodialysis graft occlusion. J Thromb Haemost 2008, Apr 2 [Electronic publication ahead of print] in press.

PII: S0049-3848(08)00240-5

doi: 10.1016/j.thromres.2008.06.020

Thrombosis Research
Volume 122 , Pages S16-S19 , 2008