Thrombosis Research
Volume 122 , Pages S1-S2 , 2008

Current status of thrombolytics—the need for better, especially safer, agents

References 

  1. Fowkes FJ, Price JF, Fowkes FG. Incidence of diagnosed deep vein thrombosis in the general population: systematic review. Eur J Vasc Endovasc Surg. 2003;25:1–5
  2. White RH. The epidemiology of venous thromboembolism. Circulation. 2003;107:I4–I8
  3. Rosamond W, Flegal K, Friday G, et al. Heart disease and stroke statistics—2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007;115:e69–e171
  4. Alkjaersig N, Fletcher AP, Sherry S. The mechanism of clot dissolution by plasmin. J Clin Invest. 1959;38:1086–1095
  5. Verstraete M. Biochemical and clinical aspects of thrombolysis. Semin Hematol. 1978;15:35–54
  6. Marder VJ. The use of thrombolytic agents: choice of patient, drug administration, laboratory monitoring. Ann Intern Med. 1979;90:802–808
  7. Marder VJ, Landskroner K, Novokhatny V, et al. Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit. Thromb Haemost. 2001;86:739–745

PII: S0049-3848(08)00237-5

doi: 10.1016/j.thromres.2008.06.008

Thrombosis Research
Volume 122 , Pages S1-S2 , 2008

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