Thrombosis Research
Volume 122, Supplement 3 , Pages S1-S2, 2008

Current status of thrombolytics—the need for better, especially safer, agents

BloodCenter of Wisconsin, Milwaukee, WI, USA

Abstract 

Clot dissolution using enzymes from the human fibrinolytic system has long been a goal of physicians and scientists. While recent focus has been on activators of the fibrinolytic system, new data support the use of plasmin itself. This supplement reviews the role of plasmin in fibrinolysis and locally administered plasmin as a safe and effective therapeutic.

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PII: S0049-3848(08)00237-5

doi:10.1016/j.thromres.2008.06.008

Thrombosis Research
Volume 122, Supplement 3 , Pages S1-S2, 2008

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