Thrombosis Research
Volume 121, Issue 2 , Pages 213-223 , 2007

Isolation and characterization of a heparin with low antithrombin activity from the body of Styela plicata (Chordata-Tunicata). Distinct effects on venous and arterial models of thrombosis

  • Joana C. Santos

      Affiliations

    • Laboratório de Tecido Conjuntivo, Hospital Universitário Clementino Fraga Filho and Instituto de Bioquímica Médica (IBqM) — Programa de Glicobiologia, Universidade Federal do Rio de Janeiro (UFRJ), Cidade Universitária, Rio de Janeiro, RJ, CEP 21941-590, Brazil
    • Contributed equally to the work.
    • ,
  • Juliana M.F. Mesquita

      Affiliations

    • Laboratório de Tecido Conjuntivo, Hospital Universitário Clementino Fraga Filho and Instituto de Bioquímica Médica (IBqM) — Programa de Glicobiologia, Universidade Federal do Rio de Janeiro (UFRJ), Cidade Universitária, Rio de Janeiro, RJ, CEP 21941-590, Brazil
    • Contributed equally to the work.
    • ,
  • Celso L.R. Belmiro

      Affiliations

    • Laboratório de Tecido Conjuntivo, Hospital Universitário Clementino Fraga Filho and Instituto de Bioquímica Médica (IBqM) — Programa de Glicobiologia, Universidade Federal do Rio de Janeiro (UFRJ), Cidade Universitária, Rio de Janeiro, RJ, CEP 21941-590, Brazil
    • ,
  • Carolina B.M. da Silveira

      Affiliations

    • Laboratório de Tecido Conjuntivo, Hospital Universitário Clementino Fraga Filho and Instituto de Bioquímica Médica (IBqM) — Programa de Glicobiologia, Universidade Federal do Rio de Janeiro (UFRJ), Cidade Universitária, Rio de Janeiro, RJ, CEP 21941-590, Brazil
    • ,
  • Christian Viskov

      Affiliations

    • Sanofi-aventis, Centre de Recherche de Paris, Unité de Glycochimie, Batiment Lavoisier 13, Quai Jules Guesde 94400 Vitry-sur Seine, France
    • ,
  • Pierre A. Mourier

      Affiliations

    • Sanofi-aventis, Centre de Recherche de Paris, Unité de Glycochimie, Batiment Lavoisier 13, Quai Jules Guesde 94400 Vitry-sur Seine, France
    • ,
  • Mauro S.G. Pavão

      Affiliations

    • Laboratório de Tecido Conjuntivo, Hospital Universitário Clementino Fraga Filho and Instituto de Bioquímica Médica (IBqM) — Programa de Glicobiologia, Universidade Federal do Rio de Janeiro (UFRJ), Cidade Universitária, Rio de Janeiro, RJ, CEP 21941-590, Brazil
    • Corresponding Author InformationCorresponding author. Instituto de Bioquímica Médica, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Caixa Postal 68041, Rio de Janeiro, RJ, 21941-590, Brazil. Tel.: +55 21 2562 2093; fax: +55 21 2562 2090.

Received 22 December 2006 ,Revised 22 December 2006 ,Accepted 30 March 2007.

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PII: S0049-3848(07)00128-4

doi: 10.1016/j.thromres.2007.03.025

Thrombosis Research
Volume 121, Issue 2 , Pages 213-223 , 2007

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