Thrombosis Research
Volume 121, Issue 2 , Pages 203-212 , 2007

VEGF increases the fibrinolytic activity of endothelial cells within fibrin matrices: Involvement of VEGFR-2, tissue type plasminogen activator and matrix metalloproteinases

  • David Ratel

      Affiliations

    • Laboratoire de Médecine Moléculaire Ste-Justine-UQAM, Centre de Cancérologie Charles-Bruneau, Hôpital Ste-Justine et Université du Québec à Montréal, 3175 Chemin Côte-Ste-Catherine, Montréal, Qc, Canada H3T 1C5
    • Present address: INSERM U318, UJFG, CHU Michallon, 38043 Grenoble, France.
  • ,
  • Samira Mihoubi

      Affiliations

    • Laboratoire de Médecine Moléculaire Ste-Justine-UQAM, Centre de Cancérologie Charles-Bruneau, Hôpital Ste-Justine et Université du Québec à Montréal, 3175 Chemin Côte-Ste-Catherine, Montréal, Qc, Canada H3T 1C5
  • ,
  • Edith Beaulieu

      Affiliations

    • Laboratoire de Médecine Moléculaire Ste-Justine-UQAM, Centre de Cancérologie Charles-Bruneau, Hôpital Ste-Justine et Université du Québec à Montréal, 3175 Chemin Côte-Ste-Catherine, Montréal, Qc, Canada H3T 1C5
  • ,
  • Yves Durocher

      Affiliations

    • Animal Cell Technology Group, Biotechnology Research Institute, National Research Council Canada, 6100 Royalmount Avenue, Montréal, Québec, Canada H4P2R2
  • ,
  • Georges-Etienne Rivard

      Affiliations

    • Service d'Hématologie-Oncologie, Hôpital Ste-Justine, Montréal, Québec, Canada H3T 1C5
  • ,
  • Denis Gingras

      Affiliations

    • Laboratoire de Médecine Moléculaire Ste-Justine-UQAM, Centre de Cancérologie Charles-Bruneau, Hôpital Ste-Justine et Université du Québec à Montréal, 3175 Chemin Côte-Ste-Catherine, Montréal, Qc, Canada H3T 1C5
    • Corresponding Author InformationCorresponding authors. Laboratoire de médecine moléculaire, Centre de recherche de l'Hôpital Ste-Justine, 3175 Chemin Côte-Ste-Catherine, Montréal, QC, Canada H3T 1C5. Tel.: +1 514 345 2366; fax: +1 514 345 2359.
  • ,
  • Richard Béliveau

      Affiliations

    • Laboratoire de Médecine Moléculaire Ste-Justine-UQAM, Centre de Cancérologie Charles-Bruneau, Hôpital Ste-Justine et Université du Québec à Montréal, 3175 Chemin Côte-Ste-Catherine, Montréal, Qc, Canada H3T 1C5
    • Service d'Hématologie-Oncologie, Hôpital Ste-Justine, Montréal, Québec, Canada H3T 1C5
    • Corresponding Author InformationCorresponding authors. Laboratoire de médecine moléculaire, Centre de recherche de l'Hôpital Ste-Justine, 3175 Chemin Côte-Ste-Catherine, Montréal, QC, Canada H3T 1C5. Tel.: +1 514 345 2366; fax: +1 514 345 2359.

Received 10 November 2006 ,Revised 2 March 2007 ,Accepted 28 March 2007.

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 This work was supported by a grant from the Canadian Institutes for Health Research to D.G. and R.B.

PII: S0049-3848(07)00126-0

doi: 10.1016/j.thromres.2007.03.024

Thrombosis Research
Volume 121, Issue 2 , Pages 203-212 , 2007