Thrombosis Research
Volume 121, Issue 2 , Pages 193-202 , 2007

Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study

  • Michael J. Stone

      Affiliations

    • Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Building 10, Room 1N306a, 10 Center Drive, Bethesda, MD 20892, USA
    • Howard Hughes Medical Institute Research Scholars Program, USA
  • ,
  • Victor Frenkel

      Affiliations

    • Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Building 10, Room 1N306a, 10 Center Drive, Bethesda, MD 20892, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 301 402 5710; fax: +1 301 496 9933.
  • ,
  • Sergio Dromi

      Affiliations

    • Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Building 10, Room 1N306a, 10 Center Drive, Bethesda, MD 20892, USA
  • ,
  • Peter Thomas

      Affiliations

    • Division of Bioengineering and Physical Science, Office of Research Services, National Institutes of Health, Bethesda, MD, USA
  • ,
  • Ryan P. Lewis

      Affiliations

    • Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Building 10, Room 1N306a, 10 Center Drive, Bethesda, MD 20892, USA
  • ,
  • King C.P. Li

      Affiliations

    • Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Building 10, Room 1N306a, 10 Center Drive, Bethesda, MD 20892, USA
  • ,
  • McDonald Horne III

      Affiliations

    • Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
  • ,
  • Bradford J. Wood

      Affiliations

    • Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Building 10, Room 1N306a, 10 Center Drive, Bethesda, MD 20892, USA

Received 12 January 2007 ,Revised 8 March 2007 ,Accepted 9 March 2007.

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 Supported in part by the Intramural Research Program, Clinical Center, National Institutes of Health; Howard Hughes Medical Institute Research Scholars Program (MJS).

PII: S0049-3848(07)00125-9

doi: 10.1016/j.thromres.2007.03.023

Thrombosis Research
Volume 121, Issue 2 , Pages 193-202 , 2007