Thrombosis Research
Volume 120, Supplement 1 , Pages S17-S20, 2007

More than menorrhagia: A review of the obstetric and gynaecological manifestations of von Willebrand disease

Women's Hemostasis and Thrombosis Clinic, Duke University Medical Center, Durham, NC 27710, USA

Abstract 

Menorrhagia is the most common symptom experienced by women with von Willebrand's disease (VWD), but several other gynaecological disorders also occur more frequently in these women; primarily ovarian cysts and endometriosis. Women with VWD are most likely to experience an increased incidence of gynaecological disorders and obstetric complications that manifest with bleeding. The incidence of these disorders and the complications of pregnancy are discussed with particular reference to a case-control study conducted by the U.S. Centers for Disease Control and Prevention.

Keywords: von Willebrand's disease, VWD, Menorrhagia, Endometriosis, Pregnancy, Postpartum haemorrhage

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PII: S0049-3848(07)00115-6

doi:10.1016/j.thromres.2007.03.012

Thrombosis Research
Volume 120, Supplement 1 , Pages S17-S20, 2007