Thrombosis Research
Volume 120 , Pages S5-S9 , 2007

The role of von Willebrand factor in thrombus formation

References 

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  2. Mendolicchio GL, Ruggeri ZM. New perspectives on von Willebrand factor functions in hemostasis and thrombosis. Semin Hematol. 2005;42:5–14
  3. Ruggeri ZM. Structure and function of von Willebrand factor. Thromb Haemost. 1999;82:576–584
  4. Wagner DD, Olmsted JB, Marder VJ. Immunolocalization of von Willebrand protein in Weibel–Palade bodies of human endothelial cells. J Cell Biol. 1982;95:355–360
  5. Bowie EJ, Solberg LA, Fass DN, Johnson CM, Knutson GJ, Stewart ML, et al. Transplantation of normal bone marrow into a pig with severe von Willebrand's disease. J Clin Invest. 1986;78:26–30
  6. Levy GG, Nichols WC, Lian EC, Foroud T, McClintock JN, McGee BM, et al. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature. 2001;413:488–494
  7. Dent JA, Berkowitz SD, Ware J, Kasper CK, Ruggeri ZM. Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. Proc Natl Acad Sci U S A. 1990;87:6306–6310
  8. Dent JA, Galbusera M, Ruggeri ZM. Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit. J Clin Invest. 1991;88:774–782
  9. Ruggeri ZM. Platelet and von Willebrand factor interactions at the vessel wall. Ha¨mostaseologie. 2004;24:1–11
  10. Ruggeri ZM. Old concepts and new developments in the study of platelet aggregation. J Clin Invest. 2000;105:699–701
  11. Ruggeri ZM, Orje JN, Habermann R, Federici AB, Reininger AJ. Activation-independent platelet adhesion and aggregation under elevated shear stress. Blood. 2006;108:1903–1910

PII: S0049-3848(07)00114-4

doi: 10.1016/j.thromres.2007.03.011

Thrombosis Research
Volume 120 , Pages S5-S9 , 2007

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