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Foreword
27 January 2012
Giovanni de Gaetano, Chiara Cerletti
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The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets
27 January 2012
Martina Nylander, Abdimajid Osman, Sofia Ramström, Emma Åklint, Anders Larsson, Tomas L. Lindahl
Abstract: Introduction: Arterial thrombi contain more platelets than venous thrombi and are more resistant to fibrinolysis. This resistance could partly be due to plasminogen activator inhibitor 1 (PA...
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Effect of the Factor Xa Inhibitor Rivaroxaban on Arterial Thrombosis in Wild-Type and Apolipoprotein E-Deficient Mice
27 January 2012
Nana-Maria Wagner, Tobias Dressel, Katrin Schäfer, Stavros Konstantinides
Abstract: Rivaroxaban is a potent and specific direct inhibitor of coagulation factor Xa. Recent studies have highlighted its effectiveness in the prevention of venous thrombosis and embolic stroke du...
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Podoplanin expression in advanced atherosclerotic lesions of human aortas
27 January 2012
Kinta Hatakeyama, Mika Kato Kaneko, Yukinari Kato, Tetsunori Ishikawa, Kensaku Nishihira, Yuta Tsujimoto, Yoshisato Shibata, Yukio Ozaki, Yujiro Asada
Abstract: Thrombus formation on disrupted atherosclerotic lesion is a key mechanism of cardiovascular events. Podoplanin (Aggrus), expressed on the surface of several tumor cells, is an endogenous lig...
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Bridging with the Low molecular weight heparin certoparin in patients requiring temporary discontinuation of oral anticoagulation – the non-interventional, retrospective REMEMBER study
27 January 2012
Ralf Eisele, Nima Melzer, Cornelia Englert, Peter Bramlage, Michael Spannagl
Abstract: Background: Bridging of a temporal discontinuation of oral anticoagulation with low molecular weight heparins (LMWH) is common practice. Specific data on the LMWH certoparin are however limi...
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